Block3 Lecture4 Flashcards

1
Q

What are the 3 types of nebulizers discussed?

A

1) biomechanical, 2) jet, 3) ultrasonic

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2
Q

how does a standard/conventional jet nebulizer work?

A

continual generation of aerosol

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3
Q

How does a breath-assisted/open-vent jet nebulizer work?

A

enhances generation of aerosol upon inhaling

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4
Q

How does a breath-activated/dosimetric jet nebulizer work?

A

generates aerosol only upon inhaling

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5
Q

For what ages of children should a full-face mask be used?

A

less than 4

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6
Q

Portable jet nebulizers are generally for children aged?

A

9 plus

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7
Q

which nebulizers do not require hand-lung coordination?

A

jet and ultrasonic

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8
Q

which nebulizer gives the smallest droplets?

A

ultrasonic

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9
Q

what are the disadvantages to an ultrasonic nebulizer?

A

cost, temperature control, oxidation

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10
Q

what is contained in an MDI?

A

drug particles suspended in volatile liquid propellant

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11
Q

What velocity does an MDI generate at the nozzle?

A

30 to 50 m/s

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12
Q

What is the particle size given by an MDI at 10 cm (the throat)?

A

12 microns

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13
Q

At what distance is the propellant completely evaporated from an MDI plume?

A

25 cm

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14
Q

Describe the emitted contents of an MDI?

A

drug and propellant

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15
Q

What is the velocity of an MDI plume at 10 cm?

A

10 m/s

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16
Q

What propellants are generally used in MDIs?

A

HFAs

17
Q

Approximately how much drug from an MDI plume ends up in the lung?

A

20 percent

18
Q

describe an open tube spacer.

A

the simplest design; sole function to increase distance

19
Q

What brand is an open tube spacer?

A

AeroChamber

20
Q

Describe a reservoir spacer.

A

aerosol directed into a chamber that holds the plume

21
Q

What brand is a reservoir spacer?

A

InspirEase

22
Q

Describe a reversed flow spacer.

A

plume directed against inhalation flow for increased propellant evaporation, completely breath activated

23
Q

What is the general function of a spacer?

A

increase distance between nozzle and oropharynx to allow propellant evaporation, smallest particle size, and better hand-lung coordination by decreasing velocity

24
Q

What are 3 DPI designs?

A

twisthaler/turbuhaler, spiriva handihaler, diskus

25
Q

What brand products use the twisthaler design?

A

symbicort, pulmicort, oxeze

26
Q

Describe the handihaler.

A

a reloadable device that uses blister pack capsules

27
Q

Describe the diskus DPI design.

A

disposable DPI that uses unit-dose blister-pack capsules

28
Q

What brands use the diskus design?

A

serevent, flovent, advair

29
Q

What particle size does an MDI produce?

A

a reproducible range