Block 5 Flashcards
What are the components of oral combination pill contraceptives.
Oestrogen and progesterone.
What is the mechanism of action of oral combination pill contraceptives?
Suppresses ovulation, and reduces LH and FSH secretion.
What drug is in oral mini-pill contraceptives?
Progesterone.
What is the mechanism of action of oral mini-pill contraceptives?
Suppresses ovulation and alters endometrium.
What drug is in implants/injectable contraceptives?
Long-acting progesterone.
What is the mechanism of action of implants/injectable contraceptives?
Suppresses ovulation.
What are the different options for HRT?
- oestrogen alone
- combined oestrogen and progestin
- selective oestrogen receptor modulators (SERMs): tamoxifen
What is the mechanism of action of using oestrogen (alone or in combination with progestin) as HRT?
Restores hormone levels.
What is the mechanism of action of selective oestrogen receptor modulators (SERMs)?
Partial agonist of oestrogen receptors.
Name a vaginally administrated drug used to induce labour.
Prostaglandin E2 (PGE2; dinoprostone).
What is the mechanism of action of prostaglandin E2 in the induction of labour?
Stimulates uterine contraction and cervical ripening.
Name an intravenously administered drug used to augment labour.
Oxytocin.
What is the mechanism of action of oxytocin in augmenting labour?
Drives myometrial contraction.
