Block 15 drug list Flashcards

1
Q

Diphenoxylate

A

Drug Class: Anti-diarrheal medication

MOA:
Diphenoxylate is an opiate receptor agonists that stimulate mu receptors in GI to decrease the peristalsis and constrict the sphincters. Diphenoxylate has a direct effect on circular smooth muscle of the bowel, that conceivably results in segmentation and prolongation of gastrointestinal transit time.

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2
Q

Loperamide

A

Drug Class: Long acting anti-diarrheal

Indication: non-specific diarrohea and chronic diarrohea

MOA:
Loperamide acts on the mu-opioid receptor expressed on the circular and longitudinal intestinal muscle
Loperamide inhibits the release of acetylcholine and prostaglandins,8 thereby reducing propulsive peristalsis and increasing intestinal transit time

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3
Q

Kaolin

A

Drug class: Natural

Indication: diarrohea, skin dryness and minor bleeding

MOA:
Kaolin adsorbs water, toxins and bacteria, contributing to firmer stools, reducing fluid loss from diarrhea.

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4
Q

Ispaghula Husk

A

Indication: Constipation

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5
Q

Lactulose

A

Drug Class: Laxative

Indication: chronic constipation

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6
Q

Bisacodyl

A

Drug Class: stimulant laxative

Indication: Occasional constipation and cleansing of colon

MOA:
Bisacodyl is deacetylated to the active bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM) by an intestinal deacetylase.4,5,6 BHPM can stimulate parasympathetic nerves in the colon directly to increase motility and secretions.5

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7
Q

Docusate

A

Drug class: Stool softener

Indication: Constipation associated with dry hard stools, and opiod induced constipation

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8
Q

Allopurinol

A

Drug class: for gout

Indication: prophylaxis of gout

MOA: reduces urinary and serum uric acid levels by inhibiting xanthine oxidase

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9
Q

Hydrocortisone

A

Weak steroid

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10
Q

Betamethasone

A

Strong steroid

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11
Q

Fludrocortisone

A

Drug class: Mineralocorticoid

Indication: adrenocortical insufficiency

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12
Q

Beclomethasone

A

Inhaled corticosteroid

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13
Q
A
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