Block 1 equations (Vd, CL, Css etc) Flashcards
1
Q
What is the equation for Volume of distribution?
A
Vd = Q/Cp
Q (amount of drug in body)
Cp (plasma conc of drug)
2
Q
What is the equation for half life of a drug?
A
3
Q
What is the equation for calculating clearance of a drug?
A
Cl = 0.7 x (Vd/t1/2)
4
Q
What is the equation for the loading dose of a drug?
A
5
Q
What is the equation for the maintenance dose of a drug?
A
6
Q
What is the equation for infusion rate?
A
IR (ko) = CL*Css
Css (steady state)
7
Q
What is the equation for Dose rate?
A
DR= Css * CL
8
Q
What is the equation for steady state (Css)?
A
Css = Ko(or DR) / Cl
Ko (rate of infusion) OR DOSE RATE
9
Q
A
