Blistering disorders

Question 1

What does the severity of the blister depend on

Answer 1

The split in the skin

Question 2

What are the 2 most common types of blistering disorders

Answer 2

Bullous pemphigoid

Pemphigus vulgaris

Question 3

What are the differences between bullous pemphigoid and pemphigus vulgaris in terms of:

a) where the antibodies target
b) blisters caused
c) mos common presenting age

Answer 3

Bullous pemphigoid

a) basment membrane
b) intact
c) old age

Pemphigus vulgaris

a) desmosomes
b) flaccid (non-intact)
c) middle-aged

Question 4

Which type of blistering disorder can affect the eyes and genital area

Answer 4

Pemphigus vulgaris

Question 5

What type of blisters does bullous pemphigoid (BP) and pemphigus vulgaris (PV) cause

Answer 5

BP -> intact

PV -> flaccid

(pemphihOOOOOid= strOOOOOng)

Question 6

What is the difference in the Nikolsky sign between bullous pemphigoid and pemphigus vulgaris

Answer 6

Bullous pemphioid -> -ve

Pemphigous vulgaris -> +ve

Question 7

What type of blistering disorder causes blisters that are often haemorrhagic and not jus fluid-filled

Answer 7

Pemphigous vulgaris