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Block 6 Exam 3 > BLI 35 - Drugs for HIV/AIDS > Flashcards

BLI 35 - Drugs for HIV/AIDS Flashcards

1
Q

Binds gp41

A

Enfuvirtide

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2
Q

Prevents interaction with gp120

A

Maraviroc

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3
Q

Fx: Protease Inhibitors inhibit _______

A

CYP3A4

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4
Q

Hyperpigmentation

A

Emtricitabine (NRTI)

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5
Q

2 drugs that decrease mother-to-newborn transmission

A

Zidovudine & Lamivudine

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6
Q

Enfuvirtide

A

Attachment and fusion inhibitor

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7
Q

2 drugs for treatment of HBV infection

A

Lamivudine

Tenofovir

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8
Q

Liver injury

3A4 & 2B6 inducer

A

Nevirapine (NNRTI)

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9
Q

Stavudine

A

NRTI

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10
Q

Predisposed to hypersensitivty if given Abcavir

A

HLA-B*5701

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11
Q

Ritonavir

A

Protease Inhibitor

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12
Q

Etravirine

A

NNRTI

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13
Q

Used in boosted therapy - combined with PIs to increase their plasma level and duration

A

Ritonavir

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14
Q

Emtricitabine

A

NRTI

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15
Q

Tenofovir

A

NRTI

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16
Q

Teratogenic

Neuropsychiatric reactions

A

Efavirenz (NNRTI)

17
Q

Maraviroc

A

Attachment & fusion inhibitor

18
Q

Zidovudine

A

NRTI

19
Q

Pancreatitis & Peripheral neuropathy

A

Didanosine (NRTI)

20
Q

What are the two single pill regimens?

A

Efavirenz-Tenofovir-Emtricitabine

Rilpivirine-Tenofovir-Emtricitabine

21
Q

Subcutaneous injection

A

Enfuvirtide

22
Q

Abacavir

A

NRTI

23
Q

Antagonist of CCR5

A

Maraviroc

24
Q

Delavirdine

A

NNRTI

25
Q

Renal impairment

A

Tenofovir (NRTI)

26
Q

Raltegravir

A

Integrease inhibitor

27
Q

Hypersensitivity rxn due to HLA-B*5701

A

Abcavir (NRTI)

28
Q

Didanosine

A

NRTI

29
Q

Efavirenz

A

NNRTI

30
Q

3 drugs used for drug-resistant strains of HIV

A

Enfuvirtide & Maraviroc (for those resistant to RTIs & PIs)

Raltegravir (for those resistant to multiple anti-retroviral agents)

31
Q

Nevirapine

A

NNRTI

32
Q

Lamivudine

A

NRTI

33
Q

Pancreatitis only

A

Stavudine (NRTI)

34
Q

Atazanavir

A

Protease Inhibitor

35
Q

Bone marrow suppression

A

Zidovudine (NRTI)

36
Q

Anything with -navir

A

Protease Inhibitor

Block 6 Exam 3 (5 decks)

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