Kasbari, Siddiqui, Rizzo Flashcards

1
Q

Process that converts centroblast to centrocyte

A

Somatic hypermutation

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2
Q

Bcl-2

A

Follicular

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3
Q

>20% blasts

A

Accelerated phase of CML

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4
Q

Chronic inflammatory states

  • Hashimoto thyroiditis
  • H. pylor gastritis
  • Sjogren
A

Marginal Zone

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5
Q

Cyclin D1+

A

Mantle Cell

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6
Q

CD5/20

A

CLL/SLL

Mantle Cell

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7
Q

Basophiles increasd

A

CML

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8
Q

Hypogammaglobulinemia

ITP & AHA

A

CLL/SLL

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9
Q

gingival hyperplasia

A

AML

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10
Q

Virus associated with mixed cellularity CHL

A

EBV

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11
Q

Tx: ATRA

A

Acute promyelocytic

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12
Q

t(2;5)

A

ALCL

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13
Q

MPO

Auer rods

A

AML

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14
Q

t(8;14)

A

Burkitt

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15
Q

Smudge cell

Soccer ball appearance

A

CLL/SLL

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16
Q

Treat with imatinib

A

CML

17
Q

TRAP

Dry tap

A

Hairy Cell

18
Q

Centroblasts

>15 = stage III

< 15 = stage I or II

A

Follicular

19
Q

2 medical emergencies

A

Burkitt

T-ALL

20
Q

Transformation of CLL

A

Diffuse Large B Cell

Prolymphocytic

ALL

21
Q

t(15;17)

A

acute promyelocytic

Subtype of AML

22
Q

Colonic perforation from Ileocecal mass

A

Burkitt

23
Q

Morphology of acute promyelocytic

A

Bilobed nuclei

Auer rods

24
Q

CD34

TdT

A

B-ALL

25
Q

Decreased Leukocyte Alkaline Phosphatase (LAP)

A

CML

26
Q

t(14;18)

A

CLL/SLL

Follicular

27
Q

Involves the jaw

A

Burkitt - Endemic (African)

28
Q

CD10/20

A

Follicular

Burkitt

B-ALL

29
Q

PML-RARA

A

Acute promyelocytic

30
Q

CD15

A

CHL

31
Q

Monocytopenia

A

Hairy Cell

32
Q

c-myc

A

Burkitt

33
Q

MALToma

A

Marginal Zone

34
Q

CD30

A

CHL

ALCL

35
Q

ALK-1

A

ALCL

36
Q

t(11;14)

A

Mantle Cell

“mante-LL –> 11”

37
Q

Good prognosis AML’s

A

t(15;17)

t(8;21)

t(16;16) or inv16

38
Q

CD23

A

CLL/SLL