Benign Hyperplasia Flashcards

1
Q

More common

Mediastinum, abdominal cavity

90% hyaline vascular type

10% plasma cell

A

Castleman Disease - Localized

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2
Q

Histology shows:

Interfollicular vascularity

Hyalinized vessels

Mantle cell lymphocytes show onion skinning

What disease is most likely?

A

Castleman Disease - Localized

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3
Q

Immunophenotype of Rosai-Dorman Disease

A

S100+

CD68+

CD1a -

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4
Q

Sinus histiocytosis with massive LAD

A

Rosai-Dorman Disease

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5
Q

Marked follicular hyperplasia

Sinusoidal dilation by monocytoid B-cells

A

Toxoplasmosis FH

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6
Q

Geographic follicles with germinal centers

Follicle lysis –> invaginating small lymphocytes in GCs

A

HIV-associated FH

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7
Q

Histolgy reveals active penetration of one cell by another which remains intact

A

Emperipolesis of Rosai-Dorman Disease

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8
Q

Small and large histiocytic aggregates within interfollicular areas and encroach upon GCs

A

Epithelioid granulomas of Toxoplasmosis FH

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9
Q

Interfollicular areas show multinucleated cells = Warthin Finkeldey cells

A

HIV-associated FH

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10
Q

Palisading histiocytes with central necrosis

A

Cat-Scratch Disease FH

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11
Q

Primary –> HHV-8

Almost all Plasma cell type

A

Castleman Disease - Multicentric (IL-6 Syndrome)

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12
Q

Which stain to detect Bartonella henselae?

A

Warthin-Starry stain

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