Bisphosphonates and MRONJ Flashcards
What are bisphosphonates primarily used for?
Bisphosphonates are primarily used to treat osteoporosis and other bone diseases.
True or False: Bisphosphonates can lead to osteonecrosis of the jaw (MRONJ).
True
Fill in the blank: MRONJ stands for _______.
Medication-Related Osteonecrosis of the Jaw
What is a common risk factor for developing MRONJ?
Dental procedures such as extractions or implants.
Multiple Choice: Which of the following is NOT a bisphosphonate? A) Alendronate B) Risedronate C) Amoxicillin
C) Amoxicillin
What is the mechanism of action of bisphosphonates?
They inhibit osteoclast-mediated bone resorption.
True or False: MRONJ can occur after dental surgery in patients taking bisphosphonates.
True
What are the clinical features of MRONJ?
Clinical features include exposed bone in the jaw, pain, and swelling.
Fill in the blank: The risk of MRONJ is higher in patients receiving _______ doses of bisphosphonates.
high
Short Answer: Name one bisphosphonate used in cancer treatment.
Zoledronic acid
Multiple Choice: Which population is at higher risk for MRONJ? A) Elderly patients B) Young athletes C) Pregnant women
A) Elderly patients
What should be done before dental surgery in patients on bisphosphonates?
Risk assessment and possible management planning.
True or False: MRONJ is reversible with treatment.
False
What is the recommended management for MRONJ?
Management may include antibiotics, oral rinses, and surgical intervention.
Fill in the blank: Bisphosphonates are often administered _______ or orally.
intravenously
Short Answer: What is one dental procedure that poses a risk for MRONJ?
Tooth extraction
What factors increase the risk of MRONJ in patients taking bisphosphonates?
Duration of therapy, route of administration, and concurrent corticosteroid use.
Multiple Choice: Which type of bisphosphonate is associated with a higher risk of MRONJ? A) Oral B) Intravenous
B) Intravenous
True or False: Patients taking bisphosphonates should avoid all dental care.
False
What is the protocol for patients on bisphosphonates prior to dental implant placement?
Consultation with the prescribing physician and careful evaluation of risks.
