bipolar disorder Flashcards

1
Q

what is bipolar affective disorder?

A

characterised by alternating periods of depressive and elevated mood (mania or hypomania)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the types go BPAD?

A

BPAD Type 1: One or more manic episodes and one or more depressive episodes.

BPAD Type 2: Recurrent major depressive episodes and hypomanic episodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how do you diagnose BPAD via ICD11?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how do you diagnose BPAD via DSM5?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is mania?

A

Severe functional impairment or psychotic symptoms persisting for at least seven days.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is hypomania?

A

Increased or decreased function for at least four days without psychotic symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

triggers for BPAD?

A

Stressful life events, physical illness, or illicit substance misuse can trigger manic episodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

medication induced causes of BPAD?

A

A ‘manic switch’ can be induced by antidepressants (e.g. SSRIs) when treating a depressive episode.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the clinical features of BPAD?

A

depressive phase, manic phase

Psychotic symptoms (delusions, hallucinations) and risk-taking behaviors (sexual disinhibition, spending/gambling, violence).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is seen in the depressive phase?

A

Low mood, feelings of worthlessness, decreased energy, and suicidal ideation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is seen in the manic phase?

A

Elevated or irritable mood, inflated self-esteem, decreased need for sleep/sleep disturbance (is both a feature of, and can precipitate manic episodes), impulsivity, pressured speech, and potential psychotic symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how do you investigate BPAD?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when does BPAD usually develop?

A

late teens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

who can manage what in BPAD?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the management of acute mania/new BPAD diagnosis?

A

STOP SSRI

mania with agitation = Intramuscular neuroleptic or benzodiazepine, potential psychiatric admission.

mania w/o agitation = Oral antipsychotic monotherapy (haloperidol, olanzapine, quetiapine, or risperidone). Potential addition of sedatives or mood stabilizers, such as lithium if antipsychotics are unsuccessful. Electroconvulsive therapy (ECT) is a last resort.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the management of acute depression/new BPAD diagnosis?

A

Mood stabilizer dose increase if alread taking. If not on established mood stabilizer, consider SSRI and atypical antipsychotic cover.

17
Q

what is chronic BPAD management?

A

4 wks post acute ep

mood stabilisers eg lithium or valproate

High-intensity Psychological Therapies: Cognitive-Behavioral Therapy (CBT), Interpersonal Therapy.

18
Q

complications of BPAD?

A

suicide risk
recurrence of manic eps

19
Q

what are the risks of BPAd with co-morbidities?

A

there is a 2-3 times increased risk of diabetes, cardiovascular disease and COPD

20
Q

what is the adntidepressant of choice in managing depressive eps?

A

fluoxetine

21
Q

what improves outcomes of BPAD?

A

Early and consistent management improves outcomes.