Bipolar Depression Flashcards
Can you have depression and mania at the same time?
Yes, known as Bipolar with mixed features
Is Bipolar disease highly recurrent when treated?
Yes, the more recurrences the higher risk
What lasts longer: depressive or manic symptoms?
Depressive symptoms last much longer.
Which two bipolar agents are the most antidepressant and least antimanic?
Lurasidone and Lamotrigine
Which 3 bipolar agents are the most antimanic and least antidepressant?
Risperidone, Paliperidone, and Abilify
What are the four FDA approved treatments for Bipolar Depression? What is one non FDA approved medication that is often used?
1) Olanzapine/Fluoxetine
2) Seroquel
3) Lurasidone
4) Cariprazine
Lamotrigine often used
What is one important educational component for patients when taking Lurasidone (Latuda)?
Must take with food, at least 350 calories
Which FDA approved treatments have the least metabolic side effects?
Cariprazine and Lurasidone
Why is Lamotrigine not approved for acute bipolar depression? What is it approved for?
Not enough evidence, it is approved for the prevention of mood episodes.
What drug interaction is important to look out for with Lamotrigine?
Valproic Acid
Is there evidence for antidepressants in bipolar depression?
May actually hasten depressive recurrence, minimal evidence for benefit
What are 4 other potential treatments for bipolar depression?
Ketamine
ECT
rTMS
Lumateperone?
