bipolar

Question 1

Anti-mania

Answer 1

lithium

Question 2

lithium

Answer 2

The therapeutic index for lithium is small, and plasma titers of Li+ must be carefully monitored
Adverse effects-
GI irritation, hand tremor, muscular weakness, polyuria, thirst, dry mouth, sleepiness, lethargy, cold feeling, hair loss, and impotence
Sodium-restricted diets → ⇑ renal retention of lithium
Thiazide diuretics → ⇑ renal retention of lithium

Question 3

Dental Complications of Schizophrenia and Bipolar Disorder

Answer 3

Antipsychotics cause extrapyramidal symptoms
Clozapine ⇢ agranulocytosis ⇢ oral candidiasis
Clozapine ⇢ hyper salivation = problem for dental procedures
Lithium for bipolar disease ⇢ xerostomia ⇢ ⇑ dental caries
NSAIDs ⇢ ⇩ renal excretion of lithium ⇢ systemic toxicity
Lithium ⇢ a metallic taste that can alter the palatability of food