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MT 11 > Biorisk Management > Flashcards

Biorisk Management Flashcards

1
Q

any microbiological entity that may have able to provoke infection, allergy, toxicity and other adverse effects in human

A

biological agent

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2
Q

examples of biological agents

A

bacteria, fungi, virus, viroid, endo-, and ectoparasites

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3
Q

Any material comprised of, containing, or that may
contain biological agents and/or their harmful products

A

biological material

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4
Q

Potential source of harm caused by biological materials

A

biohazard

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5
Q

Containment principles, technologies, and
practices implemented to prevent
unintentional/accidental exposure to
pathogens and toxins

A

Laboratory biosafety

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6
Q

protecting people from bad pathogens

A

laboratory biosafety

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7
Q

Institutional and personal security measures
designed to prevent intentional release of pathogens
and toxins

A

laboratory biosecurity

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8
Q

protecting pathogens from dangerous people

A

laboratory biosecurity

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9
Q

stealing cultures from the laboratory

A

laboratory biosecurity

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10
Q

examples of biosafety

A

engineering controls, good laboratory work practices, personal protective equipment

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11
Q

Examples of biosecurity

A

doors with locks
password/pin
biometrics
cameras
information security

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12
Q

Effect of uncertainty expressed by the combination of the CONSEQUENCES of an event and the associated LIKELIHOOD of occurrence,
where biological material is the source of harm

A

biorisk

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13
Q

System or process to control safety and security risks

A

biorisk management

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14
Q

biorisk management strategy

A
  • describe work activities
  • identify hazards & identify any threats
  • determine risks
  • decide whether the risk is acceptable or not
  • if yes,
  • proceed with work and monitor controls
  • if no
  • prepare risk control action plan
  • implement control measures
  • review adequacy of plan
  • revise or close project
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15
Q

conduct judicious evaluation of risks, selecting which mitigation measures will be employed

A

Biorisk Management Manager

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16
Q

supervises the biorisk management

A

BRM Manager

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17
Q

Influences to management decisions are:

A

Perception of risk
- risk tolerate vs risk averse influenced by:
- financial
-political
-cultural
- communication
- geography

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18
Q

Biorisk management utilize a _________ approach with a goal of continuous improvement

A

Plan-Do-Check-Act

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19
Q

It is the pinpoint areas of bio risk management that need improvements

A

plan

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20
Q

It is the trial and error section of Laboratory Biorisk Management act

A

Do

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21
Q

It is the section of LBRM of implementation (not full) of test plan or trial

A

Check

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22
Q

it is the area for full implementation

A

Act

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23
Q

-identification of potential improvement
-analysis of current situation
- development of new concepts

A

plan

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24
Q

testing and optimization of new concept

A

Do

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25
Q

careful checking of process and obtained result
-if successful, full approval

A

check

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26
Q

full implementation

A

act

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27
Q

The BRM - AMP Model

A

assessment
mitigation
performance

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28
Q

Identification of Biorisk

                                            Biosafety risk              biosecurity risk 
                                          assessment                       assessment 
                                                          

                                                      Performance Measure
A

Lab BRM
The AMP Model

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29
Q

Identify the specific hazards or threaths

determine the consequences of an identified risk

identify all the existing controls and any additional ones that need to be applied

A

risk management

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30
Q

it is an object that can cause harm

A

hazard

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31
Q

it is a person that intent to cause harm to other people

A

threat

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32
Q

it can be based either on hazard and/or threat

A

risk

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33
Q

RG 1, RG 2, RG3, and RG4

A

Agent Risk Group

34
Q

agents that are not associated with disease

A

RG1

35
Q

example of rg1 agent

A

brewer’s yeast

36
Q

agents that are associated with disease but rarely serious

A

RG2

37
Q

Examples of RG2 agents

A

herpes virus, streptococcus pneumoniae

38
Q

agents that are associated with lethal or serious disease

A

RG3

39
Q

Example of RG3 disease

A

Yersinia Pestis, HIV, SARS virus

40
Q

agents that are associated with serious disease with no therapeutic interventions

A

RG 4

41
Q

Examples of RG4 agents

A

Ebola virus, Marburg virus

42
Q

Risk Assessment Question

A

pathogen
procedures
personnel
personal protective equipment
place

43
Q

Ways of transmission of pathogens

A

direct
indirect
few-oral
percutaneous
perinatal

44
Q

is the likelihood of an event/incident with a hazard that has consequences

A

risk

45
Q

probability of an event occurring

A

likelihood

46
Q

severity of an event

A

consequence

47
Q

1 - rare
2 - unlikely
3 - possible
4 - likely
5 - almost certain

A

determining likelihood of an event

48
Q

may occur only in exceptional circumstances

A

rarely

49
Q

could occur at some time

A

unlikely

50
Q

might occur at some time

A

possible

51
Q

will probably occur in most circumstances

A

likely

52
Q

expected to occur in most circumstances

A

almost certain

53
Q

1 - insignificant
2 - minor
3 - moderate
4 - major
5 -catastrophic

A

consequences

54
Q

no injuries, low financial loss

A

insignificant

55
Q

first aid treatment, on site release immediately contained

A

minor

56
Q

medical treatment required, on site release contained with outside assistance, high financial loss

A

moderate

57
Q

extrusive injuries, loss of production capability, off site effects with no detrimental effects, major financial loss

A

major

58
Q

death, toxic release offsite with detrimental effects, huge financial loss

A

catastrophic

59
Q

lab procedures that can cause produce aerosols

A

pipetting
mixing
shaking
configuration
blending

60
Q

risk identification

hazards/threat identification

likelihood evaluation

consequences evaluation

A

assessment

61
Q

elimination or substitution

engineering controls

administrative controls

practices and procedures

PPE

A

Mitigation

62
Q

control

assurance

improvement

A

performance

63
Q

a process to identify the hazards and evaluate the risks associated with biological agents and toxins

A

assessment

64
Q

actions or control measures that are put into place to reduce or eliminate the risks

A

mitigation

65
Q

evaluating and ensuring that the system is working the way it was designed, and identifying opportunities for system improvement

A

performance

66
Q

Hierarchy of Controls

A

elimination
sublimation
engineering controls
administrative controls
ppe

67
Q

5 major categories in controlling biological risks

A

elimination or substitution

engineering controls

administrative controls

practices and procedures

personal protective equipment

68
Q

physically remove the the hazard

A

elimination

69
Q

replace the hazard

A

replace the hazard

70
Q

engineering controls

A

isolate people from the hazard

71
Q

removing the risk

A

elimination

72
Q

substitution of a serious pathogen with one this is much less pathogenic

A

substitution

73
Q

physical changes -to work stations, any relevant aspect of the work environment that reduce or prevent exposure to hazards

A

controls engineering

74
Q

policies, standards, and guidelines

A

administrative

75
Q

devices worn by the worker to protect against hazards

A

ppe

76
Q

more on equipment, materials, and production facilities

A

engineering controls

77
Q

Advantage and disadvantage of engineering controls

A

Advantage

efficient
eliminates Hazards
significantly reduces the potential and and the level of exposure to pathogens

Disadvantage
Cost
Complexity

78
Q

Advantage and disadvantage of administrative

A

Advantage

authority approach

Disadvantage

Indirect approach
Addresses human factor

79
Q

Advantage and disadvantage of practices and procedures

A

Ad.

SOP based

Dis.

Training and Supervision Required

80
Q

Advantage and disadvantage of PPE

A

Ad.
easy of use
relative cost

Dis.
does not eliminate Hazard
If ppe fails, exposure happens, uncomfortable, limits ability

MT 11 (4 decks)

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