BIOMEDICINE - JENNIFER'S CLASS NOTES Flashcards
Another name for white blood cells
Leukocytes
75% of Luekocytes are
Nuetrophils
20-40% of Luekocytes are
Lymphocytes
What do Nuetrophils do?
Bacterial infection
What are the earliest white blood cells to arrive?
Neutrophils
What are Eosinophils for?
Allergic Reaction
What are Lymphocytes for?
Viral infections, luekemia
What is Leukocytosis?
Increase in white blood cells
What is Luekopenia?
Too few white blood cells
What is the function of Hemoglobin?
Oxygen carryin gproteins
Red blood cells are called
Erythrocytes
What is the function of a platelet?
To stop bleeding
Platelets are also called
Thrombocytes
What are the structures of the external/outer ear
Auricle, Helix, Lobule
The external auditory canal is made up of
Ear wax, tympanic membrane
The tympanic membrane is also called
The eardrum
What are the structures of the middle ear?
Malleolus, incus, stapes, secondary tympanic membrane
What are the three smallest bones in the body?
Malleolus, incus, stapes
What is the inner ear called?
The labyrinth
What are the structures in the inner ear?
Choclea, cholear duct, semicircular canals and ducts, stapes in oval windows, round windows
How many lobes are in the thymus?
2
Describe the shape of the Thymus
2 lobes lying on either side of the midline of the body
Divided into small subdivisions called lobules
What is the Thymus covered in?
Dense connective tissue capsule
What does the dense connective tissue capsule do for the Thymus?
Sends fibres into the body of the thymus for support
Where are the trigeminal nerves?
The face
What does the opthalmic branch of the trigeminal nerve go to?
The eyes
If there is a problem in the opthalmic branch of the trigeminal nerve, where is the numbness?
Just below the eye around ST 2
Where does the Maxillary nerve of the Trigeminal nerve go to?
Upper jaw bone
Where does the Mandibular Nerve of the Trigeminal Nerve go to?
Lower jaw bone
Which nerve gives rise to taste?
Facial nerve VII
What are some symptoms of Bell’s Palsy
Loss of taste, decreased salivation, inability to close the eyes
What nerve is associated with bell’s Palsy
Facial Nerve VII
Which part of the brain balances the body’s position?
Cerebellum
Where is the sperm stored?
The testes or seminiferous tubules
Where is the heart located in the chest?
Between the 2nd and 6th intercostal spaces
Parasternal to the left mamillary line, in the middle of the mediastinum behind the breast bone of the chest
Level with T5 through T8
The largest part of the heart is usually located
Slightly offset to the left side of the chest
What is the lower tip of the chest called?
The apex
Where is the apex of the heart located?
Just to the left of the sternum, 8-9cm away from the midline, between the junction of the 4th and 5th ribs near their articulation with the costal cartilages
Where is the heart positioned towards?
Shaped like a cone, upwards, and tapering down to the apex
What are the two major sounds of the heart?
Lub Dub
The “lub” sound of the heart is called
S1, the first sound
The “lub”/S1 sound of the heart is caused by
Turbulence caused by the closure of the mitral and tricuspid valves at the start of systole
What is the second sound of the heart called
“Dub”, or S2
The “dub”/S2 sound of the heart is caused by
The closure of the aortic and pulmonic valves, towards the end of the systole
What is a systole?
The time period elapsing between the first heart sound and the second heart sound
A systole is also called a
Ventricular ejection
What is a diastole?
The time between the second sound of the heart and the following first sound
Diastole is also called
Ventricular filling
Which vein does not contain de-oxygenated blood?
Pulmonary vein
Blood passes from the right atrium to the
Right ventricle via the tricuspid valve/right atrioventricular valve
From the right ventricle blood passes to the
Left atrium to the left ventricle via the mitral/bicuspid valve
The left atrium receives blood from the lungs via the
Pulmonary veins (oxygenated blood)
Blood passes from the left ventricle to the
Aortic valve to the ascending aorta to the coronary arteries supplying the blood to the heart wall
What supplies blood to the heart?
Coronary arteries
Rheumatic heart disease affects which valve?
Most commonly a valve lesion in the mitral valve
How is pulmonary edema formed in the lungs?
The left ventricle fails so the blood can’t be pumped and is backed up into the lung causing edema and suffocation
How is pulmonary edema formed in the ankles and feet?
The right ventricle fails and blood backs up in the systemic veins over time and the kidneys cause an increase in blood volume resulting in peripheral edema
What is staphylococcus aureus
A purulent infection/abscess - a gram positive coccal bacteria that is a member of the Firmicutes
Where is staphylococcus aureas usually found?
In the respiratory tract or the skin (common cause of skin infections and abscesses, respiratory infections such as sinusitis, and food poisoning)
Staphyloccus aureas is often positve for
Catalase and nitrate reduction
How does staphyloccus aureas promote infections?
By producing potent protein toxins and expressinve cell surface proteins that bind and inactivate antibodies
What causes pernicious anemia?
Too little vitamin B12
Where is vitamin B12 mostly absorbed?
Illeum
What causes less pancreatic juice?
sugar
Hyperthyroid symptoms
The thyroid gland is overactive, the body’s processes are sped up causing: nervousness, anxiety, rapid heartbeat, hand tremor, excessive sweating, weight loss, sleep problems, poor concentration
What is bulging eyes as a result of hyperthyroidism?
Graves Disease
Hypothyroid symptoms
Fatigue, weakness, weight gain or increased difficulty losing weight, coarse/dry hair, dry rough and pale skin, hair loss, cold intolerance, muscle cramps and frequent muscle aches
What causes glaucoma?
Build up of aqueous humor, poor blood flow, and damage to the optic nerve
Symptoms of cholecystitis?
Gall stones, upper right abdominal pain, colic pain, light white stool colour, nausea and vomit, jaundice, cramping and bloating, pain that spreads to your back or below your right shoulder blade, fever and chills, jaundice, itching, positive Murphy’s sign, symptoms occur just after a fatty meal, (vomiting brings temporary relieve pain), fever (if the GB is infected)
What are the symptoms of a stroke?
Facial drooping, cannot raise arms, speech slurred, loss of consciousness, severe headache, coma, face red, fists clenched, breathing coarsely, gurgles sputum
Why does renal failure cause edema?
Edema occurs due to salt and water retention and metabolic ACIDOSIS due to the Kidney’s inability to excrete acidic substances
Why does renal failure lead to cardiac arrest?
The kidney can’t excrete metabolic waste products causing an increase of UREA in the body leading to POSTASSIUM levels to arise causing cardiac arrest
Why is there anemia during renal failure?
The kidneys can no longer produce enough erythropoietin for adequate RBC production
Why does osteomalacia occur during renal failure?
The kidneys are no longer able to convert Vitamin D to calcitriol which is needed for adequate absorption from the small intestine leading to osteomalacia
What is the treatment for edema?
Adequate protein and vitamin B - risk of mlanutrition
Where are RBCs destroyed?
In the liver and spleen by fixed macrophages
Where is food absorbed?
Small intestine
How long does food remain the small intestine?
3-5 hours
How long do gastrointestinal substances remain in the colon?
3-10 hours
What lymph node is enlarged for stomach cancer?
Left supraclavicular lymph node
What lymph node is enlarged for lung cancer?
Right supraclavicular lymph node
Acute Appendicitis symtpoms
Referred pain in the umbilical region, loss of appetite, nausea and vomiting, pain in the lower right quadrant (McBurney’s sign), pressure rebounding pain, worsening of pain when examination hand is placed firmly on the abdomen and suddenly removed, pain on percussion, rigidity and guarding, higher levels of Neutrophils
Where is McBurney’s point
on the right side of the abdomen, 1/3 the distance from the ASIS to the umbilicus
Which point stops facial artery bleeding?
ST 5
What can improve/increase the breathing rate?
carbon dioxide concentration
What is the temperature regulation center of the body?
Hypothalamus
Where is erythropoietin made?
The kidneys
Where does fertilization take place?
In the ampulla of the falopian tubes
The Thymus gland is part of the endocrine system but functionally more part of the
Immune system
What does the Thymus do?
Serves a vital role in the training and development of T-lymphocytes or T cells, an extremely important type of white blood cells
What do T cells do?
Defend the body from potentially deadly pathogens such as bacteria, viruses, and fungi
The parathyroid gland is least likely to develop into
Cancer
Stiffness of the neck involves which two muscles
Trapezius and SCM
What is the prostate gland?
Walnut sized gland located between the bladder and the penis
The urethra runs through the center of the
prostate
Angina pain symptoms
Occurs after exertion or emotional stress, starts in the center of the chest and spreads to the left arm, neck, back, throat, or jaw. Tightness, pressure, squeezing, or aching feeling in the chest/arms. Feeling moderate to severe indigestion that is persistent. Sharp, burning, or cramping pain. Discomfort between the shoulder blades. Numbness or a loss of feeling in your arms/shoulders/wrists.
A spider angioma is due to
Hepatocirrhosis (cirrhosis of the liver)
Body temperature from high to low
Rectum, mouth, armpit
The lowest body temperature of the day is what time?
2-6am
The highest body temperature of the day is what time?
1-6pm
What is the narrowest part of the trachea in an adult?
Rima Glottidis
What is the narrowest part of the trachea in a child?
Subglottis
What kind of cancer in the lung is most common?
Squamous cell carcinoma (25% of all lung cancers)
Symptoms of lung cancer
A cough that does not go away or gets worse, chest pain that is worse with deep breathing/coughing/laughing, hoarseness, weight loss or loss of appetite, coughing up blood or rust colored sputum (spit or phlegm), shortness of breath, feeling tired or weak
How do you calculate a person’s blood weight?
Their weight in kg x 8%
How do you calculate a person’s fluid weight?
Their weight in kg x 60%
Due date of a pregnant woman
280 days, or 40 weeks taken from the first day of her last period
Which muscle controls the adduction/inversion of the foot?
Tibialis anterior
Which muscle controls the abduction of the foot/eversio?
Peroneus longus
What nerve is damaged in drop foot?
Common peroneal nerve
What muscles support the lateral sides of the foot?
Anterior and posterior talofibular ligaments
B lymphocytes are produced in the
bone marrow
Where do B cells go from the bone marrow?
To the spleen/lymph tissues to mature into immunocompetent B cells
B cells are responsible for generating
Antibodies to specific antigens, which they bind via B cell receptors (BCR)
T cells are produced in the
Bone marrow
Where do T cells go after being produced in the bone marrow?
The thymus where they mature
Helper T cells are the major driving force and the main regulators of the
Immune defense
The primary task of the T cells is to
Activate B cells and killer T cells
Hemoptysis is found in which lung diseases
TB, pneumonia, bronchitis, lung cancer, lung abscesses
Hemoptysis is not found in
Chronic Bronchial Disease
Hemoptysis is found in which heart disease?
Mitral stenosis heart disease
The function of the gall bladder bile is to
Resolve fat (break up fat in food)
When does the growth hormone secrete the most?
During rapid wave sleep
If pressure in the brain is high it will cause
Heavy projectile vomiting
Which blood vessels nourish the liver?
Hepatic Artery (oxygenated blood) Portal Vein (deoxygenated blood)
Pancreatitis
Pancreatic cells release trypsin instead of trypsinogen
Pancreatitis symptoms
Upper left side or middle of abdomenal pain, pain is persistent and worse when lying flat on back, pain radiating to the back or below left shoulder blade, abdominal pain that feels worse immediately after eating fatty foods or alcohol, nausea, vomiting, tenderness when touching the abdomen
Black stool/melena means how much blood is in the stool?
greater than 50ml
What are all of the endocrine glands?
Thyroid Parathyroid Pituitary Adrenal Pineal