Biomed Flashcards
This antibody is most abundant (70-80%), it is the main Ig in blood, lymphs, cerebrospinal fluid, perineal fluid. It can cross the placenta so a pregnant woman can pass immunity to the fetus. It is present in plasma tissues.
IgG
This immunoglobulin is the** first to appear in response to an antigen. Though it is present in plasma, it cannot cross the placenta. It comprises 7%** of total immunoglobulins.
IgM
This immunoglobulin is frond in serum, colostrum, respiratory and intestinal mucosal membranes, saliva, and tears. It cannot cross the placenta. It is given to the baby from the mother via breast milk. Comprises 16-19% of immunoglobulins.
IgA
This is the least predominant Ig (0.01%). It is found in plasma, secretion of exocrine glands.** It promotes allergic histamine reaction.**
IgE
This is the least understood immunoglobulin. It comprises 1% of total immunoglobulins and its function is not well known. Though it serves as a receptor for B-lymphocytes.
IgD
This imaging technique is useful in the detection of pathology in the skeletal system, but may also help detect some diseases in soft tissue.
X-Ray
This diagnostic medical imaging technique is used to visualize muscles, tendons, the size, structure, and pathological lesions of many internal organs including: GB, LV, SP, HT, KD, gonads, blood vessels, lymph abnormalities, and fetal development.
Ultrasound
This medical imaging technique uses tomography where digital geometry processing is used to generate a 3D image of the internals of an object from a large series of 2D X-Ray images taken around a single axis of rotation. They may help to see tumors, blood clots, CVA, GI lesions, abdominal abscesses, biliary obstruction, aortic or cardiac aneurysms, and spinal disorders.
CT Scan
This medical imaging technique is non-invasive and is used to render images of the inside of a patient while they are stationary. This may help to view cancerous tissue, atherosclerotic tissue, joints, spine, brain, valves of the heart, tumors, tendons, and ligaments.
MRI
Increased RBC may indicate
- Polycthemia
- Renal disease
- Pulmonary disease
- CV disease
Decreased RBC may indicate
- Anemia
- Hodgkin’s Leukemia
- Sickle Cell Disease
Increased Hct and Hgb may indicate
- Dehydration
- Shock
- COPD
- CHF
- Polycthemia
Decreased Hct & Hgb may indicate
- Anemia
- Leukemia
- Hyperthyroidism
- Cirrhosis
- Massive Trauma
Increased WBC may indicate
- Acute Infection
- Neoplasm
- Leukemia
Decreased WBC may indicate
- Bone marrow problem
- Immunity problem
- Fe deficiency, ETOH
- Metastasis
- Viral infection (HIV/AIDS)
- Chemotherapy
Increased ESR may indicate
Erythrocyte Sedimentation Rate
- Kidney pathology
- Rheumatoid Arthritis, Lupus
- Thyroid disease
- Multiple myeloma
- Inflammation
- Pregnancy
Decreased ESR may indicate
- CHF
- Low plasma protein
- Polycthemia
- Sickle Cell
Higher-than-normal Iron may indicate
- Acute hepatitis
- Nephrosis
Low Iron may indicate
- Anemia
- Lupus, RA
- Hypothyroidism
- 3rd trimester of pregnancy
High BUN may indicate
Blood Urea Nitrogen
- Kidney pathology
- GI Bleed
- Heart Failure
- High-protein diet
- Dehydration
- Steroid use
Low BUN may indicate
- Pregnancy
- Malnutrition
- Liver pathology
- Acromegaly
Increased Creatinine levels may indicate
- Kidney pathology
- Hyperthyroidism
Low Creatinine levels may indicate
- Loss of muscle mass
- Aging
Increased Uric Acid may indicate
- Gout
- Arthritis
- Kidney stones/ disease
Low Uric Acid may indicate
- Chronic kidney disease
- Low thyroid
- Toxemia
- ETOH
Increased Creatine Phosphokinase (CPK) may indicate
- Myocardial Infarction
- ETOH
- Skeletal muscle disease
Increased Lactate Dehydrogenase (LDH) may indicate
- MI; pulmonary infarction
- Anemia, leukemia
- Malignancy
Decreased LDH may indicate
- Malnutrition
- Hypoglycemia
Increased GGT, AST, and ALT may indicate
Gamma-Glutamyl Transpeptidase
SGOT, Aspartate Aminotransferase
SGPT, Alanine Aminotransferase
- Liver pathology
- Cardiac muscle damage
- ETOH
- Muscle injury
- Muscular dystrophy
- Neoplasm
Decreased GGT, AST, and ALT may indicate
- Malnutrition
- Vitamin B deficiency
- Pregnancy
- Hypothalamism
- Hypothyroidism
Increased Alkaline Phosphatase may indicate
- Growing children
- Pregnancy
- Bone/liver pathology
- Gallstones
Decreased Alkaline Phosphatase may indicate
- Hypophosphatasia (genetic)
- Hypoadrenia
- Malnutrition
Increased LDL may indicate
- Atherosclerosis
- CHD - coronary heart disease
Too low LDLs may indicate
- Depression, anxiety
- Violent behavior, suicide
- Hemorrhagic stroke
Increased HDLs may indicate
- Vigorous exercise
- Insulin
- Estrogens
Too low HDLs may indicate
- Starvation
- Obesity, hypothyroidism
- Smoking
- Diabetes Mellitus, LV Disease
Increased T4 may indicate
- Hyperthyroidism
- Pregnancy
- Birth control
Low T4 may indicate
- Hypothyroidism
- Pituitary Sx
This test is most important for diagnosing LV disease
ALT
Ordering ALT with AST can help differentiate
Liver damage vs. Injury to cardiac muscle
What S/Sx would lead you to order an ALT/AST blood test for your patient?
Weakness, fatigue, anorexia, N/V, abd. swelling or pn, jaundice, dark urine, pale stool, pruritis
Hx/Family Hx of hepatitis, alcoholism, LV disease , diabetes, long-term use of medication