Biology of Orthodontic Tooth Movement Flashcards
This is the soft tissue connecting teeth to the alveolar bone; approximately 0.5mm in width
PDL
What are the four things found trapped in the PDL
Many parallel collagenous fibers
cells; fibroblasts, osteoblasts, mesenchymal stem cells, and cells from the vascular structures
blood vessels and nerve endings
tissue fluids
The PDL is constantly doing these two things
adapting and remodeling
The PDL is adapted to resist these forces
short-duration forces; it acts like a “shock absorber”
Prolongued forces induce what to occur
remodeling of the PDL and adjacent bone
6hrs = movement
These two things are important in tooth movement
force magnitude and duration
The remodeling of the PDL is mainly conducted by what
fibroblasts
This is required for tooth movement beyond the PDL space
bone resorption
These are required for bone resorption
osetoclasts
These cells are not normally available in the PDL; must be recruited from the blood vessels or bone marrow
osteoclasts
This theory states that bony changes are caused by electrical signals
bioelectric theory
This theory states that bony changes are caused by chemical signals; this theory is accepted
pressure-tension theory
What are the three proponents of the pressure-tension theory
pressure and tension alter blood flow
formation and release of chemical messengers
chemical messenger change cell activities
What is the response to 1-2 seconds of sustained light pressure
tooth displacement within the PDL space
What is the response to 3-5 seconds of sustained light pressure
blood flow changes
What is the response to minutes of sustained light pressure
oxygen tension at compression side decreases leading to prostaglandins (PG-E) and cytokines (IL-1) release
What is the response to hours of sustained light pressure
chemical messengers cause metabolic change; second messengers such as cAMP release recruiting osteoclasts
They mature and are activated leading to frontal bone resorption
What is the response to 2 days of sustained light pressure
tooth movement beyond PDL space
What is the response to 1-2 seconds of sustained heavy pressure
tooth displacement within PDL space
What is the response to 3-5 seconds of sustained heavy pressure
blood vessels occluded on pressure side