BIOLOGICAL THERAPIES FOR SZ - DRUG THERAPY

Question 1

drug therapies

Answer 1

anti-psychotic drugs - tablets, injections or syrup
short or long term as can go off without return of symptoms/have to be on them for life
split into typical and atypical anti-psychotics

Question 2

what is the typical antipsychotic for sz?

Answer 2

chlorpromazine

Question 3

there a strong association with..

Answer 3

typical anti-psychotics and dopamine hypothesis, typical anti-psychotics acts as dopamine antagonist

Question 4

what is a dopamine antagonist?

Answer 4

lower action of NT dopamine by blocking receptors in synapse of brain
first levels increase and then production is reduced

Question 5

typical anti-psychotics normalise..

Answer 5

neurotransmission in key areas of the brain and reduce symptoms such as hallucinations

Question 6

typical anti-psychotics acts as an effective…

Answer 6

sedative as it lowers anxiety, given as a syrup as it is quickly absorbed

Question 7

what is the aim of atypical drugs?

Answer 7

developing newer AP to maintain or improve the effectiveness of drugs in suppressing the symptoms of psychosis and also minimise the side effects

Question 8

what are the two types of atypical AP?

Answer 8

clozapine and risperidone

Question 9

clozapine

Answer 9

can cause blood condition of agranulocytosis
more effective that TA, small dosage and not injected
same as chlorpromazine but also acts of serotonin and glutamate improving mood and decreasing depression
usually prescribed in patient is suicidal

Question 10

risperidone

Answer 10

as effective as clozapine without side effects
bind to dopamine and serotonin
stronger effect on dopamine that clozapine
effective in small doses leading to fewer side effects