biological membranes Flashcards
describe the structure of a phospholipid
phosphate head- soluble in water, hydrophilic and polar
fatty acid tails- insoluble, hydrophobic and non-polar
give 3 roles of cell membranes
barrier between internal and external environment
location of chemical reactions
protection
why hydrophobic molecules (e.g. steroids) pass through the membrane easily
phospholipid bilayer is hydrophobic
why can water molecules pass through easily even though they are polar
they are extremely small
why does cholesterol increase the strength of the cell surface membrane
polar, hydrophilic group attracts polar phosphate heads in the phospholipids
non-polar, hydrophobic groups attracts non-polar fatty acid tails in the phospholipids
give 2 advantages of cholesterol
maintains fluidity of membrane
maintains strength
reduces the movement of water soluble chemicals
why is it called the fluid mosaic model
fluid- phospholipids can move around (flexible and can change shape)
mosaic- arrangements of proteins vary
what are intrinsic proteins
embedded in the membrane from one side to the other
how are intrinsic proteins hydrophobic
they have hydrophobic amino acid groups on the outside surface of the protein which interact with the hydrophobic fatty acid tails
what are the 2 types of intrinsic proteins
channel proteins
carrier proteins
what is the role of channel proteins
allow water soluble molecules and ions to diffuse through
why do channel proteins allow water soluble molecules to diffuse through
the central pore is lined with hydrophilic amino acids
what is the role of carrier proteins
they change tertiary shape or position to transfer ions or molecules from one side of the membrane to another side
give 3 roles of extrinsic proteins
structural role
act as enzymes
receptors (e.g. hormones)
how are extrinsic proteins different to intrinsic proteins
extrinsic don’t span the membrane whereas intrinsic proteins do
what are glycoproteins
carbohydrate molecule attached to the protein
give 3 roles of glycoproteins
allow cells to attach to each other (to make tissues)
present antigens
receptors for hormones
what are glycolipids
carbohydrate molecule attached to the phospholipid
give 3 roles of glycolipids
antigens
recognition
define diffusion
the net movement of molecules from a region of higher concentration to a region of lower concentration down a concentration gradient