Bioenergetics Flashcards
concern with the flow of energy thru the living system
Bioenergetics
ATP ____ require energy for ______, ______, ______, _______. Energy in cells is ______ largely thru ATP. Molecular unit of currency. ATP is ____ from ADP when phosphate bonds in other compounds undergo hydrolysis in _____ or in respiration. The _____ change of reaction is negative indicating that it is spontaneous.
Cells, synthesis, transport, motility, signaling, transferred, regenerated, metabolism, Free energy
Nicotinamide Adenine Dinucleotide Phosphate different from _____. NADPH is a reduced form after _____ energy. Electron donor/receptor for ______ reactions. Provides reducing power (hydrogen atoms) for ______ processes. Provides ______ for ATP formation in ______.
NAD+, expelling, oxidation-reduction, biosynthetic, electrons, respiration
process by which ATP is formed as a result of the transfer of electrons
Oxidative Phosphorylation
major source of ATP for aerobic organisms
Oxidative Phosphorylation
Three major pathways Glucose Metabolism
hexose monophosphate (HMP, also called pentose phosphate)
Entner-Doudoroff
Embden-Meyerhof- Parnas (EMP, also called glycolysis)
Primary pathway, an anaerobic pathway that terminates with the production of pyruvate.
EMP
Glycolysis Reaction
glucose + 2 Phosphate group + 2 ADP + 2NAD+ yields 2 pyruvate + 2 ATP + 2 NADH +2 H+ + 2 water
pyruvate enters TCA cycle producing carbon dioxide and NADH
Aerobic
pyruvate is converted to ethanol, lactic acid, acetone, butanol, or acetic acid (original definition of fermentation)
Anaerobic
TCA Cycle reaction
pyruvate + CoA + NAD+ yield acetyl – CoA + carbon dioxide + NADH
formed is used as reducing power to generate ATP in electron transport chain
NADH
used as a phosphoryl donor in protein synthesis and signal transduction processes or is easily interchangeable with ATP
GTP
These intermediates are replaced by anaplerotic reactions
Replenishing Intermediates
can occur by using nitrate as a terminal electron acceptor in the ETC
Anaerobic respiration