Biochem16 Flashcards

Vitamins

1
Q

What are the fat soluble vitamins?

A

A, D, E, K

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2
Q

Absorption of fat soluble vitamins are dependent on what?

A

Gut (ileum) & Pancreas

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3
Q

Toxicity is more common in fat- or water-soluble vitamins? Why?

A

Fat – accumulate in fat

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4
Q

What can cause fat-soluble vitamin deficiencies?

A
Malabsorption syndromes (steatorrhea)
 - i.e., cystic fibrosis, sprue, mineral oil intake
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5
Q

What vitamins are water soluble?

A

Vit B 1,2,3,5,6,7,9,12

Vit C

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6
Q

All water soluble vitamins easily wash out from the body except? Why?

A

Vitamin B12 & B9 (folate)

Stored in liver

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7
Q

B-complex deficiencies often result in what?

A

Dermatitis
Glossitis
Diarrhea

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8
Q

What vitamins are Antioxidants?

A

A, C, E

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9
Q

Which vitamin is a constituent of visual pigments and is essential for normal differentiation of epithelial cells into specialized tissue (pancreatic cells, mucus-secreting cells)?

A

Vitamin A

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10
Q

Retinol

A

Vit. A

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11
Q

Thiamine

A

Vit. B1

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12
Q

Riboflavin

A

Vit B2

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13
Q

Niacin

A

Vit B3

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14
Q

Pantothenic Acid

A

Vit B5

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15
Q

Pyridoxine

A

Vit B6

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16
Q

Biotin

A

Vit B7

17
Q

Folate

A

Vit B9

18
Q

Cobalamin

A

B12

19
Q

Ascorbic acid

A

Vit C

20
Q

Vit A can be used to treat what?

A
Measles
AML (subtype M3)
21
Q

Where can you obtain Vit A?

A

liver & leafy vegetables

22
Q

A deficiency in Vit A can lead to what?

A

Night blindness

Dry skin

23
Q

What is an important side effect of excess Vit A?

A

Teratogenic (cleft palate, cardiac abnormalities)

Negative pregnancy test an good contraception is required before treating women with ISOTRETINOIN for severe acne