Biochem16 Flashcards
Vitamins
What are the fat soluble vitamins?
A, D, E, K
Absorption of fat soluble vitamins are dependent on what?
Gut (ileum) & Pancreas
Toxicity is more common in fat- or water-soluble vitamins? Why?
Fat – accumulate in fat
What can cause fat-soluble vitamin deficiencies?
Malabsorption syndromes (steatorrhea) - i.e., cystic fibrosis, sprue, mineral oil intake
What vitamins are water soluble?
Vit B 1,2,3,5,6,7,9,12
Vit C
All water soluble vitamins easily wash out from the body except? Why?
Vitamin B12 & B9 (folate)
Stored in liver
B-complex deficiencies often result in what?
Dermatitis
Glossitis
Diarrhea
What vitamins are Antioxidants?
A, C, E
Which vitamin is a constituent of visual pigments and is essential for normal differentiation of epithelial cells into specialized tissue (pancreatic cells, mucus-secreting cells)?
Vitamin A
Retinol
Vit. A
Thiamine
Vit. B1
Riboflavin
Vit B2
Niacin
Vit B3
Pantothenic Acid
Vit B5
Pyridoxine
Vit B6
Biotin
Vit B7
Folate
Vit B9
Cobalamin
B12
Ascorbic acid
Vit C
Vit A can be used to treat what?
Measles AML (subtype M3)
Where can you obtain Vit A?
liver & leafy vegetables
A deficiency in Vit A can lead to what?
Night blindness
Dry skin
What is an important side effect of excess Vit A?
Teratogenic (cleft palate, cardiac abnormalities)
Negative pregnancy test an good contraception is required before treating women with ISOTRETINOIN for severe acne