Biochem part 4 Lipids Flashcards

1
Q

Type of bond that is characteristic of fats

A

Ester bonds

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2
Q

Fatty acids are composed of a (polar/ nonpolar) hydrocarbon tail and a (polar / non polar) carboxylic acid head

A

non polar tail

polar head

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3
Q

Unsaturated fatty acids contain double bonds which (increase / decrease) the melting temperature

A

Decrease the melting temperature

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4
Q

Naturally occurring double bonds exist in the ( cis / trans) configuration

A

Cis-

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5
Q

Hydrogenation of fatty acids (increases / decreases) the melting point

A

increases

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6
Q

To generate an unsaturated fat from a saturated fat, it would use a/n (Reduction / Oxidation) reaction

A

Oxidation
-losing electrons/hydrogens
“OIL”

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7
Q

the 3 essential fatty acids

A

Linoleic (omega 6)
Linolenic (omega 3)
Arachidonic (omega 6)

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8
Q

the number on the Omega; ex. omega 3, 6, 9 tells you what about the double bond

A

where the first double bond occurs

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9
Q

t/f Coconut oil is the “most saturated”

A

true

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10
Q

Which would have a higher chance of going rancid PUFAs or MUFAs

A

PUFA
the more unsaturated = greater chance of rancid
-more double bonds

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11
Q

of carbons in Lauric acid

A

12

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12
Q

of carbons in Myristic acid

A

14

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13
Q

of carbons in Palmitic acid

A

16

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14
Q

of carbons in Stearic acid

A

18

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15
Q

of carbons in Oleic, Linoleic, and Linolenic acid

A

18

  • difference is number of double bonds
  • 1, 2, 3 double bonds respectively
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16
Q

of carbons in Arachadonic acid

A

20

4 double bonds

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17
Q

Every 2 carbons in get ____ acetyl-CoA’s

A

1 acetyl CoA

18
Q

Phospholipids contain ____#___ fatty acids and a polar head group

A

2 fatty acids

19
Q

2 main classes of non glycerol lipids

A

Sphingolipids

Steroids

20
Q

The major lipid component of myelin sheath (white matter)

A

Sphingomyelin

21
Q

Most abundant sterol in humans

A

Cholesterol

22
Q

Cholesterol is derived from ______

A

Acetyl CoA

-think B5 pantothenic acid

23
Q

Rate limiting enzyme of cholesterol synthesis

A

HMG CoA reductase

-inhibited by increased levels of cholesterol

24
Q

HMG CoA reductase converts HMG CoA —-> ________

A

mevalonate

25
Q

Rate limiting enzyme in steroid biosynthesis

A

Desmolase

  • converts cholesterol —> pregnenolone
  • pregnenolone —> progesterone
  • progesterone —> all other steroid hormones
26
Q

Rate limiting enzyme of Ketone body synthesis

A

HMG CoA Synthase

27
Q

Chylomicrons are produced and secreted by what cells

A

Intestinal mucosal cells

28
Q

Chylomicrons are produced in response to the dietary intake of ______

A

Fats

-fats are absorbed and repackaged as chylomicrons

29
Q

Where do chylomicrons take triacyglycerides

A

to peripheral tissues from intestines

30
Q

VLDLs are synthesized and secreted from the ____

A

liver

31
Q

VLDL transport (exogenous/endogenous) triacylglycerides to peripheral tissues

A
Endogenous TAGs
(from liver)
32
Q

LDL is derived from ____ and transport cholesterol from the liver to peripheral tissues

A

VLDL

33
Q

Which contains the greatest amount of cholesterol; VLDL, LDL, HDL, Chylomicrons

A

LDL

34
Q

Which Lipoprotein transports cholesterol from peripheral tissues BACK to the liver

A

HDL

35
Q

Enzyme required for the uptake of triglycerides that are carried by VLDL and chylomicrons

A

Lipoprotein lipase

36
Q

Least dense lipoprotein

A

Chylomicron

37
Q

The formation of deoxyribose from ribose is what type of reaction (oxidation or reduction)

A

Reduction
-Gained a hydrogen
RIG

38
Q

Rate limiting enzyme of purine breakdown

A

Xanthine oxidase

39
Q

DNA replication occurs during the ___ phase of the cell cycle

A

S phase

40
Q

DNA replication occurs in the _____ of the cell

A

nucleus