Biochem part 2 Vitamins/minerals Flashcards

1
Q

Vit. B1 aka

A

Thiamine

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2
Q

Vit. B2 aka

A

Riboflavin

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3
Q

Vit. B3 aka

A

Niacin

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4
Q

Vit. B5 aka

A

Pantothenic acid

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5
Q

Vit B6 aka

A

Pyridoxine

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6
Q

Vit B7 aka

A

Biotin

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7
Q

Vit B9 aka

A

Folic acid/folate

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8
Q

Vit B12 aka

A

Cobalamin

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9
Q

Wernicke-Korsakoff syndrome is a result of a deficiency in _______, mostly seen in which population

A

B1 Thiamine

alcoholics

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10
Q

Beri Beri results from a deficiency in ____

A

B1 Thiamine

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11
Q

Vit B1 is involved in which type of reactions

A

Decarboxylation

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12
Q

Active form of B2 Riboflavin

A

FAD

-Flavin-adenine-dinucleotide

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13
Q

t/f B2 Riboflavin is destroyed by heat

A

False, destroyed by light

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14
Q

Magenta tongue is associated with a deficiency in ____

A

B2 riboflavin

-also angular stomatitis, cheilosis

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15
Q

Pellagra is associated with a deficiency in ____

A

B3 Niacin

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16
Q

4D’s assoc. with Pellagra

A

Dementia
Diarrhea
Dermatitis
Death

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17
Q

Active form of B3 niacin

A

NAD+ and NADP

Nicatinamide adenine dinucleotide

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18
Q

Vit B2 and B3 are both involved in which types of reactions

A

Oxidation / Reduction

Dehydrogenase enzymes

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19
Q

B3 Niacin is derived from which AA

A

Tryptophan

from nicatinamide

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20
Q

Which B vitamin is a structural component of CoA

A

B5 Pantothenic

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21
Q

Burning foot syndrome is related to a deficiency in ____

A

B5 Pantothenic

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22
Q

t/f B5 pantothenic acid is destroyed by heat

A

True

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23
Q

Transanimation reactions involve which Vitamin

A

B6 Pyridoxine
“my trans am has a B6 engine”
-Ketoacid –> Amino Acid

24
Q

B7 Biotin is involved in which type of reaction

A

carboxylation

25
Avidin found in egg whites depletes which vitamin
B7 Biotin
26
t/f B6 and B7 are made by the intestinal bacteria
True
27
B9 folic acid is involved in which type of reaction
``` Methyl transfer (one carbon transfer) -DNA and RNA synthesis ```
28
Megaloblastic anemia is associated with a deficiency in which vitamin
B9 Folic acid | -also Neural tube defects, spina bifida
29
Pernicious anemia is associated with a deficiency in which vitamin
B12 Cobalamin | -decreased intrinsic factor
30
PLS (posterolateral sclerosis) aka combined systems disease is associated with a deficiency in which vitamin
B12 cobalamin
31
Vit C enhances absorption of which mineral
Iron
32
Most active form of Vit A
retinoic acid
33
Form of Vit A involved in vision and growth
RetinAl
34
Keratomalacia is assoc. with deficiency of which vitamin
Vit A | -degeneration of the cornea
35
Excess Vit E will cause
diarrhea
36
best source of Vit E
wheat germ oil
37
Vitamin involved in blood clotting
Vit K | -production of prothrombin
38
Which vitamin is a precursor to coenzyme Q
Vit K
39
Impaired glucose intolerance may be associated to a deficiency in which mineral
Chromium - functions as a glucose tolerance factor - helps bind insulin to cell
40
t/f a function of Magnesium is binding to ATP
True
41
Deficiency of Magnesium may lead to (hyper/hypo) excitability
Hyper - binds to ATP - muscle weakness
42
Transported form of iron
transferrin
43
Storage form of iron
ferritin
44
Hypochromic microcytic anemia is associated with a deficiency of _____
iron
45
Cofactor for Carbonic anhydrase
Zinc
46
B9 gives a methyl group to ____
B12 cobalamin
47
B12 gives a methyl group to _____
Homocysteine
48
A def. of B vit. during the remethylation cycle will cause a ______ deficiency
methionine
49
t/f the methylation cycle aids in detox, DNA production and maintenance
True
50
Rate limiting enzyme in Vit D synthesis
1-alpha-hydroxylase | in kidney
51
in Vit D synthesis, Cholecalciferol is changed to 25-hydroxycholecalciferol in which organ
Liver
52
In Vit D synthesis, which organ occurs first
liver --> kidney
53
Most absorbable form of iron
Fe2+ Ferrous
54
Most active form of iron
Fe3+ Ferric
55
PTH (parathyroid hormone) (increases/decreases) serum calcium
Increases
56
Calcitonin (increases/decreases) serum calcium and is produced in what gland
Decreases -"calcitonin tones down calcium" Thyroid gland