Biochem part 2 Vitamins/minerals Flashcards

1
Q

Vit. B1 aka

A

Thiamine

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2
Q

Vit. B2 aka

A

Riboflavin

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3
Q

Vit. B3 aka

A

Niacin

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4
Q

Vit. B5 aka

A

Pantothenic acid

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5
Q

Vit B6 aka

A

Pyridoxine

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6
Q

Vit B7 aka

A

Biotin

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7
Q

Vit B9 aka

A

Folic acid/folate

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8
Q

Vit B12 aka

A

Cobalamin

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9
Q

Wernicke-Korsakoff syndrome is a result of a deficiency in _______, mostly seen in which population

A

B1 Thiamine

alcoholics

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10
Q

Beri Beri results from a deficiency in ____

A

B1 Thiamine

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11
Q

Vit B1 is involved in which type of reactions

A

Decarboxylation

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12
Q

Active form of B2 Riboflavin

A

FAD

-Flavin-adenine-dinucleotide

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13
Q

t/f B2 Riboflavin is destroyed by heat

A

False, destroyed by light

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14
Q

Magenta tongue is associated with a deficiency in ____

A

B2 riboflavin

-also angular stomatitis, cheilosis

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15
Q

Pellagra is associated with a deficiency in ____

A

B3 Niacin

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16
Q

4D’s assoc. with Pellagra

A

Dementia
Diarrhea
Dermatitis
Death

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17
Q

Active form of B3 niacin

A

NAD+ and NADP

Nicatinamide adenine dinucleotide

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18
Q

Vit B2 and B3 are both involved in which types of reactions

A

Oxidation / Reduction

Dehydrogenase enzymes

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19
Q

B3 Niacin is derived from which AA

A

Tryptophan

from nicatinamide

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20
Q

Which B vitamin is a structural component of CoA

A

B5 Pantothenic

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21
Q

Burning foot syndrome is related to a deficiency in ____

A

B5 Pantothenic

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22
Q

t/f B5 pantothenic acid is destroyed by heat

A

True

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23
Q

Transanimation reactions involve which Vitamin

A

B6 Pyridoxine
“my trans am has a B6 engine”
-Ketoacid –> Amino Acid

24
Q

B7 Biotin is involved in which type of reaction

A

carboxylation

25
Q

Avidin found in egg whites depletes which vitamin

A

B7 Biotin

26
Q

t/f B6 and B7 are made by the intestinal bacteria

A

True

27
Q

B9 folic acid is involved in which type of reaction

A
Methyl transfer (one carbon transfer)
-DNA and RNA synthesis
28
Q

Megaloblastic anemia is associated with a deficiency in which vitamin

A

B9 Folic acid

-also Neural tube defects, spina bifida

29
Q

Pernicious anemia is associated with a deficiency in which vitamin

A

B12 Cobalamin

-decreased intrinsic factor

30
Q

PLS (posterolateral sclerosis) aka combined systems disease is associated with a deficiency in which vitamin

A

B12 cobalamin

31
Q

Vit C enhances absorption of which mineral

A

Iron

32
Q

Most active form of Vit A

A

retinoic acid

33
Q

Form of Vit A involved in vision and growth

A

RetinAl

34
Q

Keratomalacia is assoc. with deficiency of which vitamin

A

Vit A

-degeneration of the cornea

35
Q

Excess Vit E will cause

A

diarrhea

36
Q

best source of Vit E

A

wheat germ oil

37
Q

Vitamin involved in blood clotting

A

Vit K

-production of prothrombin

38
Q

Which vitamin is a precursor to coenzyme Q

A

Vit K

39
Q

Impaired glucose intolerance may be associated to a deficiency in which mineral

A

Chromium

  • functions as a glucose tolerance factor
  • helps bind insulin to cell
40
Q

t/f a function of Magnesium is binding to ATP

A

True

41
Q

Deficiency of Magnesium may lead to (hyper/hypo) excitability

A

Hyper

  • binds to ATP
  • muscle weakness
42
Q

Transported form of iron

A

transferrin

43
Q

Storage form of iron

A

ferritin

44
Q

Hypochromic microcytic anemia is associated with a deficiency of _____

A

iron

45
Q

Cofactor for Carbonic anhydrase

A

Zinc

46
Q

B9 gives a methyl group to ____

A

B12 cobalamin

47
Q

B12 gives a methyl group to _____

A

Homocysteine

48
Q

A def. of B vit. during the remethylation cycle will cause a ______ deficiency

A

methionine

49
Q

t/f the methylation cycle aids in detox, DNA production and maintenance

A

True

50
Q

Rate limiting enzyme in Vit D synthesis

A

1-alpha-hydroxylase

in kidney

51
Q

in Vit D synthesis, Cholecalciferol is changed to 25-hydroxycholecalciferol in which organ

A

Liver

52
Q

In Vit D synthesis, which organ occurs first

A

liver –> kidney

53
Q

Most absorbable form of iron

A

Fe2+ Ferrous

54
Q

Most active form of iron

A

Fe3+ Ferric

55
Q

PTH (parathyroid hormone) (increases/decreases) serum calcium

A

Increases

56
Q

Calcitonin (increases/decreases) serum calcium and is produced in what gland

A

Decreases
-“calcitonin tones down calcium”
Thyroid gland