Biochem part 2 Vitamins/minerals Flashcards
Vit. B1 aka
Thiamine
Vit. B2 aka
Riboflavin
Vit. B3 aka
Niacin
Vit. B5 aka
Pantothenic acid
Vit B6 aka
Pyridoxine
Vit B7 aka
Biotin
Vit B9 aka
Folic acid/folate
Vit B12 aka
Cobalamin
Wernicke-Korsakoff syndrome is a result of a deficiency in _______, mostly seen in which population
B1 Thiamine
alcoholics
Beri Beri results from a deficiency in ____
B1 Thiamine
Vit B1 is involved in which type of reactions
Decarboxylation
Active form of B2 Riboflavin
FAD
-Flavin-adenine-dinucleotide
t/f B2 Riboflavin is destroyed by heat
False, destroyed by light
Magenta tongue is associated with a deficiency in ____
B2 riboflavin
-also angular stomatitis, cheilosis
Pellagra is associated with a deficiency in ____
B3 Niacin
4D’s assoc. with Pellagra
Dementia
Diarrhea
Dermatitis
Death
Active form of B3 niacin
NAD+ and NADP
Nicatinamide adenine dinucleotide
Vit B2 and B3 are both involved in which types of reactions
Oxidation / Reduction
Dehydrogenase enzymes
B3 Niacin is derived from which AA
Tryptophan
from nicatinamide
Which B vitamin is a structural component of CoA
B5 Pantothenic
Burning foot syndrome is related to a deficiency in ____
B5 Pantothenic
t/f B5 pantothenic acid is destroyed by heat
True
Transanimation reactions involve which Vitamin
B6 Pyridoxine
“my trans am has a B6 engine”
-Ketoacid –> Amino Acid
B7 Biotin is involved in which type of reaction
carboxylation
Avidin found in egg whites depletes which vitamin
B7 Biotin
t/f B6 and B7 are made by the intestinal bacteria
True
B9 folic acid is involved in which type of reaction
Methyl transfer (one carbon transfer) -DNA and RNA synthesis
Megaloblastic anemia is associated with a deficiency in which vitamin
B9 Folic acid
-also Neural tube defects, spina bifida
Pernicious anemia is associated with a deficiency in which vitamin
B12 Cobalamin
-decreased intrinsic factor
PLS (posterolateral sclerosis) aka combined systems disease is associated with a deficiency in which vitamin
B12 cobalamin
Vit C enhances absorption of which mineral
Iron
Most active form of Vit A
retinoic acid
Form of Vit A involved in vision and growth
RetinAl
Keratomalacia is assoc. with deficiency of which vitamin
Vit A
-degeneration of the cornea
Excess Vit E will cause
diarrhea
best source of Vit E
wheat germ oil
Vitamin involved in blood clotting
Vit K
-production of prothrombin
Which vitamin is a precursor to coenzyme Q
Vit K
Impaired glucose intolerance may be associated to a deficiency in which mineral
Chromium
- functions as a glucose tolerance factor
- helps bind insulin to cell
t/f a function of Magnesium is binding to ATP
True
Deficiency of Magnesium may lead to (hyper/hypo) excitability
Hyper
- binds to ATP
- muscle weakness
Transported form of iron
transferrin
Storage form of iron
ferritin
Hypochromic microcytic anemia is associated with a deficiency of _____
iron
Cofactor for Carbonic anhydrase
Zinc
B9 gives a methyl group to ____
B12 cobalamin
B12 gives a methyl group to _____
Homocysteine
A def. of B vit. during the remethylation cycle will cause a ______ deficiency
methionine
t/f the methylation cycle aids in detox, DNA production and maintenance
True
Rate limiting enzyme in Vit D synthesis
1-alpha-hydroxylase
in kidney
in Vit D synthesis, Cholecalciferol is changed to 25-hydroxycholecalciferol in which organ
Liver
In Vit D synthesis, which organ occurs first
liver –> kidney
Most absorbable form of iron
Fe2+ Ferrous
Most active form of iron
Fe3+ Ferric
PTH (parathyroid hormone) (increases/decreases) serum calcium
Increases
Calcitonin (increases/decreases) serum calcium and is produced in what gland
Decreases
-“calcitonin tones down calcium”
Thyroid gland