Biochem

Question 1

Main stimulator signaling the pancreas to release bicarb.

Answer 1

Secretin

Question 2

2 major enzymes that digest lipids in the intestines.

Answer 2

1. Pancreatic lipase

2. Colipase

Question 3

Salivary and pancreatic amylase hydrolyze which bond in carb digestion.

Answer 3

alpha 1,4 bond in starch

Question 4

What bond does the sucrose-isomaltase complex hydrolyze?

Answer 4

alpha 1,6 found in the dextrans and branches of starch

Question 5

Enzyme absent in lactose intolerance and the bond it cleaves.

Answer 5

Beta-glycosidase (lactase)

-cleaves beta 1,4 bond

Question 6

Transporter that allow fructose to enter intestinal cells.

Answer 6

GLUT-5

Question 7

Enzyme that cleaves trypsinogen into trypsin.

Answer 7

Enteropeptidase

Question 8

Enzyme that activates all the pancreatic zymogens.

Answer 8

Trypsin

Question 9

What kind of transporter allow glucose to enter intestinal epithelium?

Answer 9

A sodium/glucose symporter

-uses facilitated diffusion to exit the cell

Question 10

What kind of transporter allow Amino Acids to enter intestinal epithelium?

Answer 10

A sodium/AA symporter

-uses facilitated diffusion to exit the cell

Question 11

Transporter that allow larger proteins to enter intestinal epithelium (di- or tripeptides)

Answer 11

PepT transporter

Question 12

How are lipids digested, transported into intestinal cells, and then sent into the blood stream?

Answer 12

Lipids are broken down to fatty acids by lipases.
FA are emulsified by bile salts and able to diffuse into intestinal cells.

The tri-glycerides are then reformed and packaged into either VLDLs or chylomicrons and sent into lymphatics thru lacteal and then into the blood

Question 13

Condition that results from a lack of Microsomal Triglyceride Transfer Protein (MTP) activity.

Answer 13

Abetalipoproteinemia - patients have caloric deficiency and steatorrhea

Question 14

Which condition leads to a lack of transporters to absorb neutral AA?

Answer 14

Hartnup’s Disease