Bio Review and Intro Flashcards
The total risk of genetic mutation or a malignancy appearing in a certain population; used when data on radiation doses is available; predicts that a specific number of excess malignancies will occur as a result of exposure
Absolute risk
The amount of energy per unit mass absorbed by the irradiated object; expressed in the SI unit—gray (Gy), or in the traditional unit—rad
Absorbed dose
The transfer of x-ray energy to the atoms of the biologic matter through which it passes
Absorption
The result of whole-body exposure to large doses of ionizing radiation (1 Gy [100 rad] or more) over a short period
Acute radiation syndrome (ARS)
Filters added outside the glass window of the x-ray tube housing above the collimator shutters
Added filtration
A scatter-reducing technique in which the image receptor is moved 10 to 15 cm away from the patient to allow low-energy scattered x-rays from the patient to be absorbed in the air before reaching the film
Air-gap technique
Constructive metabolism
Anabolism
The third phase of mitosis, in which the duplicated centromeres travel along the mitotic spindle to opposite sides of the cell.
Anaphase
A thyroid cancer study that consisted of individuals who had received radiation doses of 0.2 to 0.3 Gy (20 to 30 rad) to the thyroid gland shortly after birth for thymic enlargement caused by infection
Ann Arbor Series
A simple beam limitation device consisting of a flat piece of lead with a hole of a designated size and shape cut through it.
Aperture diaphragm
A nonmitotic or nondivision form of cell death that occurs when cells die without attempting division during the interphase portion of the cell life cycle; also called programmed cell death or interphase cell death
Apoptosis
Basic building blocks of all matter, including human tissue
Atoms
The 22 pairs of human chromosomes that are not sex chromosomes
Autosomes
Another name for use factor
Beam-direction factor
Device that limits a patient’s exposure to unnecessary x-rays by confining the primary beam to the area of clinical interest, thereby limiting the amount of body tissue irradiated
Beam-limitation device
Committee on the Biological Effects of Ionizing Radiation
BEIR Committee
A form of acute radiation syndrome that occurs when an individual receives a whole-body dose of ionizing radiation of 1 to 10 Gy (100 to 1000 rad); also known as hematopoietic syndrome.
Bone marrow syndrome
A protective shield that covers the Bucky slot opening in the side of the x-ray table during a fluoroscopic examination when the Bucky tray is moved to the foot end of the table
Bucky slot cover
An organic compound responsible for providing the body with fuel for energy and serving as a structural component of cell walls and the material between cells. Carbohydrates consist entirely of carbon, oxygen, and hydrogen
Carbohydrate
The development of cancer
Carcinogenesis
Cancer-causing agents
Carcinogens
Solid tumors that start in the epithelial tissue; one of the two major categories of cancers
Carcinomas
Portable multiposition device often used in the operating room for orthopedic procedures; produces real-time (motion) images of a patient
C-arm fluoroscopy unit
Destructive metabolism
Catabolism
The barrier between the cell interior and the outside environment that regulates the materials passing into and out of the cell.
Cell membrane
One one-hundredth (1/100) of a gray; also equal to one rad. The centigray is replacing the rad for recording absorbed dose in therapeutic radiology.
Centigray (cGy)
A form of acute radiation syndrome that occurs when an individual receives a whole-body absorbed dose of ionizing radiation above 50 Gy (5000 rad); also known as cerebrovascular syndrome
Central nervous system syndrome
The two hollow, cylindrical structures that result from the division of the centrome
Centrioles
The clear region on a chromosome that connects chromatids
Centromere
The central body of a cell, critical to cell reproduction, which contains the centrioles
Centrosome
A form of acute radiation syndrome that occurs when an individual receives a whole-body absorbed dose of ionizing radiation above 50 Gy (5000 rad); also known as central nervous system syndrome
Cerebrovascular syndrome
A tightly coiled strand of DNA; also called daughter chromosome
Chromatid
Tiny, rod-shaped structures composed of genes
Chromosomes
Procedure using a movie-camera device (used most often in cardiology and neuroradiology); makes serial radiographic images that are recorded over a short time and then played back through a projector to allow study of motion within the patient
Cinefluorography
Shield (often used for breast and gonad shielding) made from a transparent plastic material containing 30% lead by weight; also called Lucite-Pb-equivalent shield
Clear-lead shield
Scattering that results when a low-energy x-ray photon interacts with an atom and the atom responds by releasing the excess energy it has received in the form of a scattered x-ray photon
Coherent scattering
Scattering that results when an incoming x-ray photon interacts with a loosely bound outer-shell electron, dislodges it from its orbit, and then continues in a new direction
Compton scattering
A type of beam-limitation device that confines the radiographic beam to a certain area; consists of a circular metal tube that attaches to the x-ray tube housing or variable rectangular collimator to limit the x-ray beam to a predetermined size and shape.
Cone
Areas occupied by employees who have been trained in radiation protection procedures and who wear radiation monitoring devices
Controlled area
The effect of ionizing radiation on DNA and other macromolecules after main-chain scission, which causes spur-like molecules on a molecular chain to stick to the molecular chain or to other molecules. See also main-chain scission.
Cross-linking
A radiation protection device used during fluoroscopy that either sounds an alarm or interrupts the x-ray beam after the fluoroscope has been activated for 5 minutes to ensure that the operator is aware of the ON time of the beam
Cumulative timer
The nickname for an ionization chamber type of gas-filled radiation detector; one of the two primary types of gas-filled radiation detectors
Cutie pie
The protoplasm that exists outside the nucleus of a cell.
Cytoplasm
Small components of cells contained in the cytoplasm that perform many functions of the cell.
Cytoplasmic organelles
The two sets of chromatids that develop during mitosis
Daughter chromosomes
A pregnancy that has been reported to a radiographer’s supervisor
Declared pregnancy
Instrument that measures the degree of blackening or density on radiographic film to determine the amount of radiation received and the energy of that radiation
Densitometer
The essential ingredient in chromosomes and carrier of the genetic code for cell reproduction and cell activity
Deoxyribonucleic acid (DNA)
Biologic somatic effects of ionizing radiation that exhibit a threshold dose below which the effect does not normally occur and above which the severity of the biologic damage increases as the dose increases
Deterministic effects
The formation resulting when two adjacent chromosomes that are struck in the G1 phase join during the S phase of interphase; dicentric chromosomes generally result in cell death
Dicentric chromosome
Process by which ionized particles directly transfer energy to important macromolecules, resulting in the breaking of chemical bonds, which may cause biologic damage
Direct action
The most common type of gene mutation; expressed in the first generation; examples include Huntington’s chorea, polydactyly, and retinoblastoma
Dominant gene mutation
The dose measurement that reflects the type and energy of an ionizing radiation, resulting in a measurement of the effective absorbed dose; expressed as sieverts in SI units or as rems in traditional units
Dose equivalent (DE)
The decrease in mutations as a radiation dose is given over a longer period of time
Dose-rate effect
Relationship between levels of radiation doses and the degree of observed biologic response
Dose-response relationship
The dose of ionizing radiation that would produce twice the frequency of genetic mutations as expected to occur naturally
Doubling dose
A condition caused by a chromosomal aberration involving the presence of an extra chromosome 21
Down syndrome
The atomic number calculated for human tissue, based on the many various chemical elements of which the tissue is composed
Effective atomic number
The upper boundary dose of ionizing radiation that will result in a negligible risk of bodily injury or genetic damage to the recipient
Effective dose-equivalent (EDE) limit
A system that provides a method for assessing radiation exposure and associated risk of biologic damage to radiation workers and the general public; this method determines the various risks of cancer and genetic effects to tissue and organs exposed to radiation
Effective dose-equivalent (EDE) limiting system
A measurement calculated from the type of radiation to be given and the variability of tissue and organs intended to absorb that radiation
Effective dose
A method used to protect against irradiation of an unsuspected pregnancy; requires the referring physician or radiologist to determine the time of the patient’s previous menstrual cycle
Elective booking
Solutions that can conduct electricity
Electrolytes
Network of small tubes spread throughout a cell that serve as transportation routes
Endoplasmic reticulum
The simplest and most frequently used method for reporting patient skin dose, usually measured with a thermoluminescent dosimeter (TLD)
Entrance skin exposure (ESE)
Protein that controls important chemical reactions within a cell by functioning as a catalyst; also known as enzymes
Enzymatic protein
A type of red blood cell; the most numerous of all blood cells
Erythrocytes
A measurement of radiation; expressed as coulombs per kilogram (C/kg) of air in SI units or as roentgens (R) in traditional units
Exposure
A radiation measurement calculated by dividing exposure by a unit of time
Exposure rate
A type of beam-limitation device that confines the radiographic beam to a certain area; consists of a cylindrical metal tube with a 10- to 20-inch metal extension at the far end of the barrel to limit the size of the useful beam
Extension cylinder
A personnel monitoring device that uses radiation dosimetry film in a lightweight plastic film holder containing filters of aluminum or copper to measure whole-body radiation accumulated at a low rate over a long time (usually 1 month)
Film badge
Elements that are part of, or added to, the x-ray tube to reduce exposure to the patient’s skin and superficial tissues
Filtration
Uncontoured protective shield constructed of lead strips or lead-impregnated materials placed over a patient to protect areas of the body that do not need to be examined; available in a number of shapes
Flat contact shield
A monitor that emits a beeping signal directly proportional to the exposure rate—that is, the beeping speeds up and slows down as the exposure rate increases and decreases—to help the radiographer determine the best place to stand to reduce exposure
Fluoroscopic exposure monitor
A dead-man type of foot pedal that shuts off the x-ray beam if the operator becomes incapacitated during a fluoroscopic procedure
Fluoroscopic exposure switch
A radiation dose delivered over time in equal fractions
Fractionated dose
An atom or molecule with a single electron in its outer shell
Free radical
The phase of cell life cycle prior to the synthesis of DNA in which a cell prepares for mitosis by manufacturing protein and RNA molecules
G2 phase
One of the two primary types of radiation survey instruments; uses a gas-filled chamber to measure radiation; capable of measuring the total quantity of electrical charge produced by the ionized gas or the rate at which the electrical charge is produced
Gas-filled radiation detector
A form of acute radiation syndrome that occurs in humans when an individual receives a whole-body threshold dose of ionizing radiation of approximately 6 Gy (600 rad)
Gastrointestinal syndrome
One of the two primary types of gas-filled radiation detectors; detects individual radioactive particles or photons; often used in nuclear medicine facilities
Geiger-Muller (G-M) detector
The over-expression of a gene that occurs when there are extra copies of the proto-oncogene in a cell. See proto-oncogenes
Gene amplification
A specific section on a chromosome, the DNA double helix that contains a specific sequence of nitrogenous organic bases that is related to a particular characteristic; the basic unit of heredity
Gene
A key suppressor gene; unlike other suppressor genes, gene p53 also kills malignant cells
Gene p53
Patients, visitors, and anyone else not trained to work with radiation
General public
An individual’s unique genetic makeup, as determined by the sequence of the nitrogenous organic bases in each gene
Genetic code
Damage to a cell’s ability to reproduce, which occurs after a cell has divided at least once; also called mitotic death
Genetic death
The effects of ionizing radiation on future generations
Genetic effects
The dose equivalent to the reproductive organs for the entire gene pool; if received by every human, this dose would be expected to cause gross genetic injury to the total population
Genetically significant dose (GSD)
The study of the inheritance of characteristics
Genetics
In mammography, the possible biologic response is related to glandular dose (which varies with variations in x-ray beam quality and quantity), not the skin dose. The glandular dose, in screen-film mammography, is approximately 15% of the entrance skin dose
Glandular dose
Tiny sacs located near the nucleus and tubes extending from the cell nucleus to the cell membrane; used both to make glycoproteins and to transport enzymes and hormones from the cell nucleus to the blood stream
Golgi apparatus
SI unit for absorbed dose; named for Louis Harold Gray, a British radiobiologist; equal to 100 rads
Gray (Gy)
Device placed between the patient and the film to remove scattered x-ray photons that emerge from the patient before they reach the film; improves image quality
Grid
A form of acute radiation syndrome that occurs when an individual receives a whole-body dose of ionizing radiation of 1 to 10 Gy (100 to 1000 rad); also known as bone-marrow syndrome
Hematopoietic syndrome
The maintenance of the body’s internal temperature through perspiration and respiration
Homeostasis
H2O2, a toxic substance that is poisonous to human cells
Hydrogen peroxide
A combination that can occur during radiolysis of water. Hydrogen free radicals interact with molecular oxygen
hydroperoxyl radical
International Commission on Radiological Protection
ICRP
International Commission on Radiation Units and Measurement
ICRU