bio exam 3 Flashcards
Catabolic
Released energy stored in chemical bonds
Anabolic
Input of energy
Stores in chemical bonds
Energy
Potential
Kinetic
Thermodynamics
Study of energy transformation
Entropy
Energy transfer of energy increases the entropy of the universe
Free energy
The energy avalaible to so work ( usable energy)
Total energy
Usable energy plus unusable energy
Enthoy (H)
Total energy
Free energy (G)
Usable energy
Entropy (S) x Temp (T)
Unusable energy
If G=H-TS
Change in (triangle) G= T(change in) S
So H=g+TS
G=h-TS
Negative (G<0)
Free energy is released (exergonic)
Positive (G>0)
Free energy is consumed
Enndergonic reaction
Catabolic reactions
Release free energy = exergonic
Anabolic
Consume free energy = enderfonic
ATP
Captures and transfers free energy
Phosphorylate
ATP can donate phosphate groups to other molecules the transfer if free energy
Hydrolysis of ATP
ATP+H20
Adp+P+ free energy
Exergonic reaction
Releases energy
Cell respiration
carabolisim
Endergonic reaction
Requires energy
Active transport
Cell movements
Anabolism
Transport work
ATP phosphorylates transport proteins
Mechanical work
ATP binds noncovalently to moot proteins and this is hydrolyze a
Catalyst
Speed up rate of chemical reactions
Enzymes
Activation energy
Exergonic reactions can be slow because if an energy barrier
Amount of energy requires to start the reaction (E)
Activation Energy
Enzymes lower the activation energy by bringing reactants together
Uncatalyst activation energy
Takes longer
Catalyst activation energy
Activation energy with enzyme is lower
Enzymes can strech
The bonds in substrate molecules, making them unstable
Enzymes can temporarily
Add chemical groups to substrates (makes substrate more chemically reactive)
Every enzyme is most active at a certain
Ph
(Influences functional groups
-Tempuratyre- if too high bonds break enzymes denature
IsoZymes
Enzymes that catalyze the same reaction but have different properties
(Optimal temperature)
Organsim is can use isozymes
To adjust to temperature changes
Cofactors
Nonprotein enzyme helpers
Coenzyme
Organic cofactors
Includes vitamins
Enzyme inhibitors
Molecules that bind to the enzyme and slow reaction rates
Regulate matabolisim
Competitive and noncompetitive enzyme inhibitors
Can be reversible (temporarily binds- common in organisms) or irreversible ( common in artificial )
Irreversible inhibitor
Permanently inactivated enzymes
Competitive inhibitor
Similar to natural substrate
Competes for binding site
When concentration of competitive inhibitor is reduced, it detaches from the active site
Noncompetitive inhibitor
Bind to the enzyme at a site other than the active site
- enzyme changes shape, natural substrate cannot “fit”
Detaches when concentration is reduced
Allosteric Regulation
May inhibit or stimulate enzymes activity
-activator- stabilizes active form
Inhibitor- stabilizes inactive form
(4 leaf clover)
Feedback inhibition
The end product of a metabolic pathway shuts down the pathway
Prevents waste of resources
Cellular respiration (Aerobic)
Complete oxidation
Waste product -h20, C02
Net energy- 32 ATP
Fermentation (anaerobic)
Incomplete oxidation
Waste products- lactic or ethonal and CO2
Net energy-2
Fuels
Organic compounds whose stored energy can be released for use
-glucose
Glucose- exergonic-ATP
C6H12o6—6CO2 +6H20+energy
Exergonic
Reduction
Gain of one or more electron
Oxidation
Loss of one or more electrons
Cellular respiration 4 stages
Glycolysis
Pyruvate oxidation
Citrix acid cycle
Oxidative phaophorylayion
Energy pay off
Glucose uses 2 ATP to make 2 pyruvate+ H20=ATP
4Atp formed - 2ATP used= 2 ATP
2NAD+4e+4H+= 2nadh +2h+
Energy investment phase
Uses 2atp to start
6 o2
Pyruvate oxidation
Links glylysis to Citric acid cycle
Pyruvate gets converted to 2 acetyl Coenzyme A
2 nad+ comes and gets it’s electrons transport protein comes and takes 2 carbon
Citric acid cycle 1
input- acetyl CoA, water and electron
Carriers NAD+, FAD, GDP
Citric acid cycle 2
Energy released is captured by adp and electron carriers 3 nad+, Fad, and GDP
citric acid cycle 3
Outputs 4 Co2 1ATP 3NADH 1FADH2 Per glucose molecule
Oxidative phosphorylation
Electron transport chain
Chrismioamosis
Nash and fadh2
Transport electrons to the electron transport chain
In cristae
Output 6 water , 32 ATP ,6 c02
Fermentation
Without o2 fermentation follows glyoloysis
Substrate level phosphorylation forms smaller amounts of ATp
Occurs I cytoplasm
Two types of fermentation
Alcohol
Lactic acid
Alcohol fermentation
Input - 2 pyruvate, loses 2 carbon and Evonne’s 2 acetaldehyde, 2nad+, 2adp
Ethanol end product
C6 H12 o6 +2 Adp + 2 p
= 2 ethanol + 2co2 + 2 ATP
Lactic acid fermentation
Occurs In microorganisms and some muscle cells
Input - 2 pyruvate ,2nad+2adp
Output 2atp. And 2 lactic acid
Yogurt cheese ,3 carbon
Cam plants use
Crawsulacean acid matabolisim to fixate carbon