Bio Exam Flashcards
What is science
The observation, identification, experimental investigation, and theoretical explanation of natural phenomena
What is the scientific method
Standard approach practiced by scientists
Evolution
heritable change in a population of organisms from generation to generation
structure and function
structure determines function
information
Genetic material provides a blueprint for all of the above; offspring are similar to parents
Energy and matter
Energy is acquired from the environment and used to make molecules and maintain an organisms body
Systems
Interactions between parts create novel structures or functions, leading to emergency properties
hypothesis
A proposed explanation for natural phenomenon
theory
A broad explanation of some aspect of the natural world, backed by extensive evidence
Scientific method steps
observation question hypothesis experiment analysis conclusion
peer review process
The researcher
the editor
the reviewer
scientists behind covid sequencing
Dr. Zhang Yongzhen
Dr. Edward Holmes
Scientists behind the covid vaccines
Dr. Katalin Karliko
Dr. Andrew Weissman
Dr. Kizzmekia Corbett
population
a group of individuals of the same species inhabiting the same area; potential for interbreeding
Charles Darwin
proposed that all species of life descended from common ancestor
theory of natural selection
natural selection
The process which eliminates individuals that are less likely to survive in a particular environment. Species that adapt or traits have successful reproduction
variation in traits
heritable traits passed from parent to offspring; genetic
how do characteristics get changed in species overtime
mutations accumulate in genetic material overtime
vertical evolution
occurs within a lineage. the process whereby an ancestral species changes through time (without splitting) to become distinctively different, and therefore recognized as a new species; phyletic evolution.
Atavistic trait
an ancestral trait that reappears after having been lost through evolutionary change. Example: dolphins having hind limbs.
Horizontal gene transfer
is the non-sexual movement of genetic information between genomes. Incoming DNA or RNA can replace existing genes, or can introduce new genes into a genome.
cells
simplest, functional unit of a living organism
Cell theory
- All living organisms are composed of one of more cells
- Cells are the smallest unit of life
- new cells come only prom pre-existing cells by cell divison
Who discovered the endoplasmic reticulum
Keith Porter
Plasma membrane
Barrier
attachment
cell communication
Nucleus
Genetic material
RNA
Ribonucleic acid
Single stranded
Ribosomes
Synthesizes polypeptides
endoplasmic reticulum
stores calcium needed for nerves
Rough ER
ribosomes-RNA- Site of protein synthesis
Smooth ER
Detoxification
Calcium storage
Cell membrane
Phospholipid bilayer
embedded with proteins
What is the three layers of a cell
- plasma membrane
- ACE-2 receptor binds to angiotensin- protein complex in plasma membrane
- Cytoplasm
how does a virus enter the cell
- Binds to ACE-2 receptor
- viral genetic material (RNA)
- hosts ribosomes (Make viral protein)
- -Hosts endoplasmic reticulum (modifies viral proteins
- hosts Golgi apparatus and (packages viral proteins)
- Hosts cell membrane (releases new viruses into the body)
eukaryotic cell
internal compartmentalization
prokaryotic
lack of internal compartmentalization
plant cells
cell wall
chloroplasts
Golgi apparatus
processing, modification, sorting and secreting molecules produced in that cell
where is heritable change found
in a population through generations
what is information flow
expression of genetic material and heritable transmission to offspring
the nucleus of a cell contains what
DNA
what does DNA contain
hereditary material
what does RNA support
proteins calles histones
What is cytogenetics
the cytological approach to genetics, mainly involving microscopic studies of chromosomes
Transmission genetics
The study of mechanisms involved in the passage of genes from one generation to the nest
Population genetics
The study of variation at the genetic level among a group of individuals
Quantitive trait genetics
a quantitive trait is a measurable trait that shows continuous variation and cannot be classified into a few discrete classes
Molecular genetics
The study of the molecular processes underlying gene structure
epigenetic
The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself
Genomics and bioinformatics
Study of an organisms entire compliment of genes, and use of high-performance computing to analyze sequence data
Four criteria necessary for genetic material
Information
Replication
Transmission
Variation
What are nucleotides
The building blocks of DNA and RNA
What is a “strand” of DNA
A linear polymer strand of DNA and RNA
What is a double helix
the two strands of DNA
What are chromosomes
DNA associated with an array of different proteins into a complex structure
What is a genome
The complete complement of genetic material in an organism
what is the difference between DNA and RNA
DNA is double stranded and base paired
RNA is single stranded and single stranded
What is Central Dogma
DNA replication
What is the process of central Dogma
DNA Transcrition mRNA Translation Polypeptide
What is the process of Information Flow
DNA
RNA
protein
What is a chromosome made of
Genes which are made of DNA
what does the karyotype do
Reveals number, size, and form of chromosomes in an actively dividing cell
how many pairs of sex chromosomes do humans have
one haploid pair (n)
How many pairs of chromosomes does a human have
23 diploid pairs (2n)
pair of chromosomes that are not identical are called
homologous pairs
Autosomes
each homolog nearly identical in size and genetic composition
What happens in G1 phase
Cell growth, passes restriction point, cell becomes committed to enter S phase
What happens in S phase
chromosomes replicate and are called sister chromatids
what happens in G2 phase
Cell synthesizes proteins for mitosis and cytokinesis
What is cytokinesis
follows mitosis to divide the cytoplasm into two daughter cells
How does a cell decide to divide
External factors: environmental conditions, signalling molecules
Internal factors: cell cycle control molecules, checkpoints
What are checkpoint proteins called
Cyclins or cdks
Where are chromatids tightly associated at
centromere
what is the kinetochore
centre of chromatid
mitotic spindle
Responsible for organizing and sorting the chromosome during mitosis.
What is the spindle formed from
microtubules
What are microtubules formed from
tubulin
Three types of microtubules
~Astral microtubules- position spindle in cell
~Polar microtubules- separates two poles
~kinetochore microtubules- attached to kinetochores bound to centromeres
What happens in prophase
chromatids condense into highly compacted structures
pro metaphase
mitotic spindle is fully formed during this phase. centrosome move apart and democrats the two poles
what happens metaphase
pairs of sister chromatids are aligned along a halfway between the poles called the metaphase plate
what happens in anaphase
each individual chromatid is linked to only one pole by kinetochore microtubules
what happens in telophase
chromosomes have reached their respective poles and decondense
what happens in cytokinesis
two nuclei are segregated into separate daughter cells
how is the cytokinesis process different between animal and plant cells
animal cells form a cleavage furrow and plant cells form a cell plate
how does the meiosis process start
haploid cells are produced from cell that was originally diploid
what are the two key differences in meiosis
homologous pairs form a bivalent or tetrad
crossing over
What is a bivalent trend in meiosis
when two homologous chromosomes begin synapsis and form a bivalent