bio chapter 3 Flashcards
RNA world hypothesis
Some people believe that because RNA has properties of both DNA and proteins
**folks think RNA was the original information—storage molecule
Promoters
regions of typically a few hundred base pairs where RNA polymerase and associate proteins bind to the DNA complex
terminators
transcription stops here, and the transcript stops
replication
allows the genetic inofrmation from one DNA molecule to be copied into that of another DNA molecule
Mutation
a rare error that can take place in DNA replication, a change in the genetic information in DNA
Prokaryotic Transcription/Translation
occurs in the cytoplasm
Eukaryotic transcription/translation
transcription occurs in the nucleus and translation occurs in the cytoplasm. Different from prokaryotes because it has different levels of specialization prokaryotes cant do`
Base stacking
occurs because the nonpolar, flat surfaces of the bases tend to group together away from water molecules, and hence stack on top of one another as tightly as possible
Supercoiling
the circular molecule coils upon itself, kind of like a rubber band when you twist it in your finger.
**caused by enzymes called topoisomerases that cleave, partially unwind, and reattach a DNA strand, which puts strain on the DNA double helix, then relieve the strain and help preserve the 10 base pairs per turn
topoisomerases
the enzyme that causes supercoiling
nucleosome
10 nm- chromatin fiber composed of a beadlike repeating unit
transcription
a molecule of DNA is used as a template to generate a molecule of RNA “same language at this point”
Translation
2nd step in readout of genetic information
** a molecule of RNA “translates” into the language of proteins, (used as a code for the sequence of amino acids in a protein)
nucleotides
DNA’s subunits,
consist of: a 5-carbon sugar, base, one or more phosphate groups
RNA splicing process of intron removal, catalyzed by a complex of RNA and protein known as the spliceosome
process of intron removal, catalyzed by a complex of RNA and protein known as the spliceosome