BIO 205 PROTEIN STRUCTURE Flashcards

Question 1

Q

polypeptides are

Answer

A

chains of amino acids linked by peptide bonds

Question 2

Q

amino acid formula

Answer

A

H
             |
H2N -- C -- COOH
             |
            R

R= side-chain group

Question 3

Q

unique R groups defining..

Answer

A

specific amino acids

Question 4

Q

amino acid at pH 7

Answer

A

H
                  |
(+) H3N -- C -- COO (-)
                  |
                 R

Question 5

Q

formation of a polypeptide via peptide bond

Question 6

Q

condensation of 2 amino acids == dipeptide

Answer

A

together by amide linkage

- remove 1 water molecule

Question 7

Q

Polar amino acids - Hydrophilic/Hydrophobic

Answer

A

Hydrophilic

Question 8

Q

NonPolar amino acids - Hydrophilic/Hydrophobic

Answer

A

Hydrophobic

Question 9

Q

Asparatic acid

Answer

A

[Asp]
acidic
neg polar, hydrophilic

Question 10

Q

Glutamic acid

Answer

A

[Glu]
acidic
neg polar, hydrophilic

Question 11

Q

Arganine

Answer

A

[Arg]
basic
pos polar, hydrophilic

Question 12

Q

Lysine

Answer

A

[Lys]
basic
pos polar, hydrophilic

Question 13

Q

Histidine

Answer

A

[His]
basic
pos polar, hydrophilic

Question 14

Q

Asparagine

Answer

A

[Asn]

uncharged polar, hydrophilic

Question 15

Q

Glutamine

Answer

A

[Glu]

uncharged polar, hydrophilic

Question 16

Q

Serine

Answer

A

[Ser]

uncharged polar, hydrophilic

Question 17

Q

Threonine

Answer

A

[Thr]

uncharged polar, hydrophilic

Question 18

Q

Tyrosine

Answer

A

[Tyr]

uncharged polar, hydrophilic

Question 19

Q

Alanine

Answer

A

[Ala]

non polar, hydrophobic

Question 20

Q

Glycine

Answer

A

[Gly]
non polar, hydrophobic
SMALLEST ; only H

Question 21

Q

Valine

Answer

A

[Val]

non polar, hydrophobic

Question 22

Q

Leucine

Answer

A

[Leu]

non polar, hydrophobic

Question 23

Q

Isoleucine

Answer

A

[Ile]

non polar, hydrophobic

Question 24

Q

Proline

Answer

A

[Pro]

non polar, hydrophobic

Question 25

Q

Phenylalanine

Answer

A

[Phe]

non polar, hydrophobic

Question 26

Q

Methionine

Answer

A

[Met]

non polar, hydrophobic

Question 27

Q

Tryptophan

Answer

A

[Trp]

non polar, hydrophobic

Question 28

Q

Cysteine

Answer

A

[Cys]

non polar, hydrophobic

Question 29

Q

unfolded protein

Answer

A

disordered, high entropy

- few non covalent (enthalpies) interactions

Question 30

Q

folded protein

Answer

A

highly ordered, low entropy

- many non covalent interactions

Question 31

Q

forces that determine protein folding into its native 3-D structure

Answer

A

covalent bonding
hydrogen bonding
van der waals
hydrophobic effects