Bile Acid Sequestrants Flashcards
1
Q
Bile Acid Sequestrants medications
A
Cholestyramine
Colestipol
colesevelam
2
Q
MOA
A
exchange chloride ion for bile acid in intestine, disrupt recycling of bile acids
hepatic cells convert cholesterol stores to bile acid
increase hepatocyte LDL receptors = decrease LDL
3
Q
side effects
A
abdominal pain
bloating
constipation
4
Q
Drug interactions
A
interfere with absorption of
- vitamins AEDK
- warfarin
- BB
- Levothyroxine
- thiazide diuretics
5
Q
Ease of dosing/cost
A
Dosing is a bit complicate
Expensive
