BI232 Aggressive Lymphomas Flashcards
what are the types of biopsies?
1) Fine needle aspirate
2) core biopsy
3) excisional biopsy
which type of biopsy is always preferred?
exicisional
what is seen under the microscope in hodgkin lymphoma?
reed sternberg cells
Describe the Ann-Arbor staging system
1) Stage 1 - one enlarged lymph node or one extranodal site
2) Stage 2 - multiple enlarged lymph nodes on the same side of the diaphragm
3) Stage 3 - multiple enlarged lymph nodes on both sides of the diaphragm
4) stage 4 - presence of distant extranodal disease
what are the risk factors associated with hodgkin lymphoma?
1) EBV
2) immunosuppression/HIV
3) autoimmune diseases
at what ages is hodgkin lymphoma prevalent?
1) 20-30
2) 60-80
what is the most common presentation of hodgkin lymphoma?
asymptomatic lympadenopathy
What is the treatment cocktail used to treat hodgkin lymphoma?
ABVD
A - doxorubicin (adriamycin)
B - Bleomycin
V - vincristine
D - Dexamethasone
what is the prognosis of hodgkin’s lymphoma?
good prognosis with >90% survival in patients with limited stage disease. survival of 70-80% in patients with advanced disease
what type of aggressive lymphoma is most common?
Diffuse Large B-cell Lymphoma
which of the aggressive lymphomas are the most aggressive?
Burkitt lymphoma
what are some risk factors for developing DLBCL?
HIV, UV light, Pesticides, EBV
What is the treatment for DLBCL
CHOP + R
what is the prognosis of someone diagnosed with DLBCL?
lifespan is within months if not treated
TRUE or FLASE: 60-200 times the incidence of DLBCL in HIV positive patients
TRUE
