Beta Lactam ABs Flashcards
Penicillins: different group names
Narrow spectrum
Penicillinase-stable
Broad spectrum
Against Pseudomonas
Beta-Lactamase Inhibitors
Clavulanic acid
Sulbactam
Tazobactam
Cephalosporins: how many generations
Generations 1-4
Carbapenems
Imipenem
Meropenem
Monobactams
Aztreonam
Tigemonam
What is special about Gen 3 and 4 Cephalosporins?
CIA
What is the mode of action of Beta-lactam AB?
Time-dependent bactericidal
What is the mechanism of action of Beta-lactam AB?
Inhibition of cell wall synthesis
What is the mode of action of Penicillins?
Time-dependent bactericidal
What is the mode of action of Cephalosporins?
Time-dependent bactericidal
What is the mode of action of Carbapenems?
Time-dependent bactericidal
What is the mode of action of Monobactams?
Time-dependent bactericidal
What is the mechanism of action of Penicillins?
Inhibition of cell wall synthesis
What is the mechanism of action of Cephalosporins?
Inhibition of cell wall synthesis
What is the mechanism of action of Monobactams?
Inhibition of cell wall synthesis
What is the mechanism of action of Carbapenems?
Inhibition of cell wall synthesis
Name the Narrow spectrum penicillins
Benzylpenicillin-Na, K
Benzylpenicillin-Procaine
Benzylpenicillin-benzathine
Phenoxymethy-penicillin
Name the penicillinase stable penicillins
Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin
Name the broad spectrum penicillins
Amoxicillin
Ampicillin
Name the penicillins against Pseudomonas
Ticarcillin
Piperacillin
1st Generation Cephalosporins
Cephazoline
Cephapirin
Cefadroxil
Cephalexin
2nd Generation Cephalosporins
Cefuroxime
3rd Generation Cephalosporins
Ceftiofur Cefovecin Ceftriaxone Cefotaxime Ceftazidime Cefoperazone
4th Generation Cephalosporins
Cefquinome
Amoxicillin-Clavulanic acid administration route in swine?
PO
Cefquinome administration route in swine?
IM
Ceftiofur administration route in swine?
IM
Cefadroxil belongs to which group?
Generation I. Cephalosporin
Which of the following combo would you recommend in pneumonia in dogs? A) AmoxiClav + Enrofloxacin B) AmoxiClav + Cefuroxime C) Both of them D) None of them
C) Both of them
AmoxiClav belongs to which AMEG group?
AMEG C
Which bacteria CANNOT produce beta lactase enzyme?
Streptococcus suis
Which drug is NOT authorised for poultry in the EU?
AmoxiClav
What is Ceftiofur-HCl turned into?
Desfuroyl-Ceftiofur quickly in the body
Which agent would be first line in acute pharyngitis in dogs?
Penicillin
Which drug belongs to first line treatment of pyoderma in dogs?
Cefovecin
Imipenem belongs to?
Carbapenem
Dicloxacillin belongs to?
Penicillinase-resistant penicillins
Which generation of cephalosporins does Ceftiofur belong to?
3rd Generation
Which AMEG group and generation does Cefquinome belong to?
AMEG B
4th Generation
Which cephalosporin belongs to the first line treatment of pyoderma in dogs?
Cefalexin
Cefoperazon belongs to which generation of Cephalosporins?
3rd Generation
This drug can effectively be used in cystitis in dogs if its caused by enterococci or lactamase producing E. coli?
Amoxicillin clavulanic acid and Amoxicillin
This drug is authorised for poultry and can be effective against fowl cholera?
Amoxicillin
This drug is authorised for poultry and can be effective against ulcerative enteritis?
Phenoxymethylpenicillin
True or False:
Amoxicillin is authorised only for intramuscular administration in both swine and cattle.
False
True or False:
In case of bovine P. Multocida respiratory disease the MIC value for ceftiofur is 0.004 mg/𝞵l. The concentration reached in the PELF, in the blood and in the pulmonary interstitial fluid is higher than the MIC value for more than 8 days. This means a correct drug choice for the treatment of the infectious disease.
True
