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Prudent Use of AB > Beta Lactam ABs > Flashcards

Beta Lactam ABs Flashcards

1
Q

Penicillins: different group names

A

Narrow spectrum
Penicillinase-stable
Broad spectrum
Against Pseudomonas

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2
Q

Beta-Lactamase Inhibitors

A

Clavulanic acid
Sulbactam
Tazobactam

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3
Q

Cephalosporins: how many generations

A

Generations 1-4

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4
Q

Carbapenems

A

Imipenem

Meropenem

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5
Q

Monobactams

A

Aztreonam

Tigemonam

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6
Q

What is special about Gen 3 and 4 Cephalosporins?

A

CIA

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7
Q

What is the mode of action of Beta-lactam AB?

A

Time-dependent bactericidal

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8
Q

What is the mechanism of action of Beta-lactam AB?

A

Inhibition of cell wall synthesis

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9
Q

What is the mode of action of Penicillins?

A

Time-dependent bactericidal

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10
Q

What is the mode of action of Cephalosporins?

A

Time-dependent bactericidal

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11
Q

What is the mode of action of Carbapenems?

A

Time-dependent bactericidal

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12
Q

What is the mode of action of Monobactams?

A

Time-dependent bactericidal

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13
Q

What is the mechanism of action of Penicillins?

A

Inhibition of cell wall synthesis

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14
Q

What is the mechanism of action of Cephalosporins?

A

Inhibition of cell wall synthesis

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15
Q

What is the mechanism of action of Monobactams?

A

Inhibition of cell wall synthesis

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16
Q

What is the mechanism of action of Carbapenems?

A

Inhibition of cell wall synthesis

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17
Q

Name the Narrow spectrum penicillins

A

Benzylpenicillin-Na, K
Benzylpenicillin-Procaine
Benzylpenicillin-benzathine
Phenoxymethy-penicillin

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18
Q

Name the penicillinase stable penicillins

A

Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin

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19
Q

Name the broad spectrum penicillins

A

Amoxicillin

Ampicillin

20
Q

Name the penicillins against Pseudomonas

A

Ticarcillin

Piperacillin

21
Q

1st Generation Cephalosporins

A

Cephazoline
Cephapirin
Cefadroxil
Cephalexin

22
Q

2nd Generation Cephalosporins

A

Cefuroxime

23
Q

3rd Generation Cephalosporins

A 
Ceftiofur
Cefovecin
Ceftriaxone
Cefotaxime
Ceftazidime
Cefoperazone
24
Q

4th Generation Cephalosporins

A

Cefquinome

25
Q

Amoxicillin-Clavulanic acid administration route in swine?

A

PO

26
Q

Cefquinome administration route in swine?

A

IM

27
Q

Ceftiofur administration route in swine?

A

IM

28
Q

Cefadroxil belongs to which group?

A

Generation I. Cephalosporin

29
Q 
Which of the following combo would you recommend in pneumonia in dogs?
A) AmoxiClav + Enrofloxacin
B) AmoxiClav + Cefuroxime
C) Both of them
D) None of them
A

C) Both of them

30
Q

AmoxiClav belongs to which AMEG group?

A

AMEG C

31
Q

Which bacteria CANNOT produce beta lactase enzyme?

A

Streptococcus suis

32
Q

Which drug is NOT authorised for poultry in the EU?

A

AmoxiClav

33
Q

What is Ceftiofur-HCl turned into?

A

Desfuroyl-Ceftiofur quickly in the body

34
Q

Which agent would be first line in acute pharyngitis in dogs?

A

Penicillin

35
Q

Which drug belongs to first line treatment of pyoderma in dogs?

A

Cefovecin

36
Q

Imipenem belongs to?

A

Carbapenem

37
Q

Dicloxacillin belongs to?

A

Penicillinase-resistant penicillins

38
Q

Which generation of cephalosporins does Ceftiofur belong to?

A

3rd Generation

39
Q

Which AMEG group and generation does Cefquinome belong to?

A

AMEG B

4th Generation

40
Q

Which cephalosporin belongs to the first line treatment of pyoderma in dogs?

A

Cefalexin

41
Q

Cefoperazon belongs to which generation of Cephalosporins?

A

3rd Generation

42
Q

This drug can effectively be used in cystitis in dogs if its caused by enterococci or lactamase producing E. coli?

A

Amoxicillin clavulanic acid and Amoxicillin

43
Q

This drug is authorised for poultry and can be effective against fowl cholera?

A

Amoxicillin

44
Q

This drug is authorised for poultry and can be effective against ulcerative enteritis?

A

Phenoxymethylpenicillin

45
Q

True or False:

Amoxicillin is authorised only for intramuscular administration in both swine and cattle.

A

False

46
Q

True or False:
In case of bovine P. Multocida respiratory disease the MIC value for ceftiofur is 0.004 mg/𝞵l. The concentration reached in the PELF, in the blood and in the pulmonary interstitial fluid is higher than the MIC value for more than 8 days. This means a correct drug choice for the treatment of the infectious disease.

A

True

Prudent Use of AB (5 decks)

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