Benign vulval disease

Question 1

What percentage of dVIN develops into vulval cancer?

Answer 1

33% and 80% of SCC related to dVIN.

Question 2

What is the risk of malignant transformation of LS?

Answer 2

2-5%

Question 3

What is the pathognomonic feature of lichen planus?

Answer 3

Wickham striae - fine white and grey lines on the top of the papular rash.

Question 4

What causes lichen planus?

Answer 4

T-cell autoimmune disease which can cause plaques, erosions and ulcers.

Question 5

What is the cause of Becet’s disease?

Answer 5

systemic vasculitis of small, medium and large vessels.

Question 6

What is necessary for the diagnosis of Becet’s disease?

Answer 6

Oral ulcers plus any 2 of:
-genital ulcers
- eye lesions - uveitis, retinal vasculitis.
-skin lesions - erythema nodosum, pseudofolliculitis.
-positive pathery test.

Question 7

What are the progression/regression rates of CIN?

Answer 7

CIN1: Progression 1%, Regression 57%
CIN2: Progression 5%, Regression 43%
CIN3: Progression 10-30%. Regression 32%