Benign Skin Lesions Flashcards

1
Q

what are benign skin lesions?

A

Seborrhoeic keratoses

Viral warts

Cysts

Dermatofibroma

Lipoma

Vascular lesions

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2
Q

what ar premalignant skin lesions?

A

Bowens disease

Actinic Keratoses

Melanoma in situ

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3
Q

benign lesions

A
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4
Q

Are Seborrhoeic Keratoses benign or maligant?

A

benign but commonly referred?

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5
Q

what are Seborrhoeic Keratoses?

A

They are benign growths due to a build-up of skin cells

Warty growths, “stuck on appearance”

Can have variable appearance

Patients often have multiple +/- cherry angiomas

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6
Q

what is the treatment of Seborrhoeic Keratoses?

A

• Generally left untreated, but if troublesome

  • Cryotherapy
  • Curettage
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7
Q

what is cryrotherapy?

A

Liquid nitrogen

Cryotherapy is the use of low temperatures in medical therapy. Cryotherapy may be used to treat a variety of tissue lesions

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8
Q

what are the pros of Cryotherapy?

A

Cheap

Easy to perform “on the day”

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9
Q

what are the cons of Cryotherapy?

A

Can scar

Failure/Recurrence

No pathology result

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10
Q

what is and what are the signs of Leser-Trelat?

A

Paraneoplastic phenomenon

Abrupt onset of widespread seborrhoeic keratosis, particularly in a younger individual

SKs remain benign but may indicate underlying solid organ malignancy - GI adenocarcinoma

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11
Q

what are viral warts and what causes them?

A
  • Due to Human Papilloma Virus
  • Rough hyperkeratotic surface
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12
Q

what is the treatment of viral warts?

A
  • Difficult to treat - Do we need to treat at all?
  • Will clear when immunity developed to virus
  • Cryotherapy or wart paints can stimulate immune system slightly
  • Can curette in severe cases - surgical instrument designed for scraping or debriding biological tissue or debris in a biopsy, excision, or cleaning procedure
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13
Q

what are cysts?

A
  • Encapsulated lesion containing fluid or semi-fluid material
  • Usually firm and fluctuant
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14
Q

are cysts common or rare?

A

Common

Affect ~20% adults

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15
Q

multiple different types of cysts exist, what are they?

A
  • Epidermoid cyst (often wrongly called sebaceous)
  • Pilar cyst
  • Steatocystoma
  • Dermoid cyst
  • Hidrocystoma
  • Ganglion cyst
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16
Q

what can happen tocysts which is dangerous?

A
  • Can rupture and cause inflammation of surround skin
  • May become secondary infected
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17
Q

what is the treatment of cysts?

A
  • Treated with excision
  • If inflammed/infected
  • Antibiotics
  • Intralesional steroid
  • Incision & Drainage
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18
Q

what is a Dermatofibroma?

A
  • Benign fibrous nodule, often on limbs - Proliferation of fibroblasts
  • Firm nodule, tethered to skin but mobile over fat. Pale pink/brown. Often paler in centre.
  • Dimple sign positive
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19
Q

what cause dermatofibromas?

A

Cause is unknown. They are sometimes attributed to an area of trauma

20
Q

what are the symptoms and treatments of a dermatofibroma?

A

Usually asymptomatic. Can be itchy or tender

Excision if concern or symptomatic.

21
Q

what is a lipoma, what causes it and is it common or rare?

A
  • Benign tumour consisting of fat cells
  • Common
  • Cause unknown
  • Smooth and rubbery subcutaneous mass

benign tumor made of fat tissue, usually occur jsut under the skin

22
Q

what are the symptoms of a lipoma?

A
  • Usually asymptomatic
  • If tender:
  • ?angiolipoma
  • ?Liposarcoma – rare malignancy
23
Q

what is an angioma?

A

Angiomas are benign tumors derived from cells of the vascular or lymphatic vessel walls (endothelium) or derived from cells of the tissues surrounding these vessels

Overgrowth of blood vessels in the skin due to proliferating endothelial cells

It is a vascular lesion

24
Q

what are the symptoms of an angioma?

A

Generally asymptomatic. Can be unsightly or bleed

25
who is at risk of an angioma?
Occur in all age groups, both sexes Pregnancy & liver disease
26
what is the treatment of an angioma?
Excision or laser
27
what is a Pyogenic Granuloma?
reactive proliferation of capillary blood vessels. It presents as a shiny red lump with a raspberry-like or minced meat-like surface Rapidly enlarging red/raw growth, often at a site of trauma Bleed easily Cause is unknown Occur in up to 5% of pregnancies Common on head and hands
28
what is the treatment of a pyogenic granuloma?
Removed by curettage & cautery
29
pre-malignant lesions
30
what is a pre-malignant lesion?
If premalignant then it is entirely in the epidermis and as soon as it goes into dermis it becomes an invasive malignancy
31
what are risk factors for pre-malignant skin lesions?
UV radiation - DNA damage and immunosuppression
32
what is Bowen’s Disease?
• aka Intraepidermal squamous cell carcinoma - Full thickness dysplasia, entirely contained within the epidermis, no metastatic potential - Potential to become malignant (around 5%) • Irregular, scaly erythematous plaque
33
what is the treatment of Bowens?
* Cryotherapy * Curettage - Lesion scraped off and heat applied to seal vessels and destroy residual cancer cells * Photodynamic therapy * Imiquimod
34
What is Photo-Dynamic Therapy?
* Photochemical reaction to selectively destroy cancer cells * Topical photosensitising agent applied - Concentrates in cancerous cells (due to higher metabolic rate) * Red light applied (light colour dependant on which agent is used) * Photodymanic reaction occurs between light, photosensitiser and oxygen causing inflamation and destruction of cells
35
what are the pros of photodynamic therapy?
Done for the patient by hospital staff Can treat multiple areas, including those which would be hard to reach by patient Requires 1 or 2 treatments
36
what are the cons of photodynamic therapy?
Requires hospital appointments Can be painful and scar
37
what is imiquimod
* Aldara * Immune response modifier - Stimulates cytokine release * Inflammation and destruction of lesion topical treatment
38
what are the pros of imiquimod?
- Useful where surgery is undesirable - Usually good cosmetic result - Large surface area
39
what are the cons of imiquimod?
- Treatment time is 6 weeks - Significant inflammation - Failure/recurrence
40
what is Actinic Keratoses?
Rough scaly patches on sun damaged skin a rough, scaly patch on your skin that develops from years of exposure to the sun
41
what is the risk of Actinic Keratoses transforming to SCC?
Low risk of transformation to SCC - If average of 7.7 AK, the probability of developing an SCC within 10 years is 10%
42
whatis the treatment of Actinic Keratoses?
* May spontaneously resolve * Treatment - Cryotherapy - Curettage - Diclofenac Gel - Imiquimod
43
what is a Melanoma in situ?
Melanoma cells entirely confined to epidermis No metastatic potential Treated with excision
44
what is Lentigo Maligna?
* Type of melanoma in situ * Usually facial Lentigo maligna is a melanoma in situ that consists of malignant cells but does not show invasive growth
45
what ways is there for sun protection?
* Cover up * Avoid sun at peak hours - 10am-4pm * Don’t burn and try not to tan * Avoid sunbeds * Sunscreen: - UVA & UVB protection - At least SPF 30/4 Star (for UVA) - Need to apply 2 tablespoons every 2 hours