Benign Renal Tumors (Chap 90 12th ed)

Question 1

Which cystic kidney disease is associated with significant malignancy risk?

Answer 1

Acquired cystic kidney disease.

Question 2

Most common benign renal tumor

Answer 2

Renal cyst

Question 3

Most common benign enhancing renal mass

Answer 3

Renal oncocytoma

Question 4

What syndrome is associated with renal oncocytoma and what are its characteristics?

Answer 4

Oncocytomas are histologically similar to chromophobe renal cell
carcinoma (RCC), and immunohistochemical staining may be
required to distinguish the two.
Oncocytoma is associated with Birt-Hogg-Dubé syndrome:
characterized by pulmonary cysts, spontaneous pneumothoraces,
and fibrofolliculomas.
When suspected, a percutaneous biopsy may provide a diagnosis
when core tissue is available for additional immunohistochemical
studies.

Question 5

Most common cause of retroperitoneal spontaneous hemorrhage? How do you treat it? In what syndrome is it common?

Answer 5

AML
Treat with selective angioembolization
Tuberous sclerosis

Question 6

What pathway is followed by AML pathology, and what meds are given?

Answer 6

mTOR pathway

Everolimus

Question 7

What is a benign renal tumor that can cause secondary hypertension?

Answer 7

Renal juxtaglomerular cell apparatus