Behcet's Disease Flashcards
1
Q
Define Behcet’s Disease?
A
An inflammatory multisystem disease that often presents with orogenital ulceration and uveitis
2
Q
What is the aetiology of Behcet’s Disease?
A
Associated with HLA-B51
3
Q
What is the epidemiology of Behcet’s Disease?
A
More common in Turkey, Greece and Central Asia
4
Q
What are the presenting symptoms and signs of Behcet’s Disease?
A
Recurrent ORAL and GENITAL ulceration Uveitis Skin Lesions (e.g. erythema nodosum) Arthritis Thrombophlebitis Vasculitis Myo/Pericarditis CNS symptoms Colitis
5
Q
What investigations do you do for Behcet’s Disease?
A
Diagnosis is very CLINICAL
Pathergy Test
You may measure complement levels and check for a positive family history
6
Q
What is the Pathergy Test?
A
A needle prick becomes inflamed and a sterile pustule develops within 48 hrs
