Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Behavioral Health > Behavioral Health Meds 2 > Flashcards

Behavioral Health Meds 2 Flashcards

1
Q

Imipramine is useful for _____ and _____

A

Enuresis in children and panic disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the least sedating and least anticholinergic TCA?

A

Desipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which TCA is the least likely to cause orthostatic hypotension?

A

Nortriptyline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which TCA is best tolerated?

A

Nortriptyline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

______ is good for smoking cessation

A

Bupropion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bupropion causes less ___, ____ and ____ than SSRIs (AEs)

A

Sexual dysfunction, weight gain and GI effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Bupropion MOA

A

Dopamine and norepinephrine reuptake inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Bupropion indicated for?

A

MDD and SAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Bupoprion AKA

A

Wellbutrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a serious neurological AE of bupropion?

A

Lowers seizure threshold

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are AEs of Wellbutrin? (7)

A

-Dry mouth
-Nausea
-Insomnia
-Agitation
-Weight loss
-HTN
-HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Bupropion can increase risk of _____ at high doses

A

Psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Avoid ___ _____ in Bupropion

A

abrupt withdrawl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When is Bupropion contraindicated?

A

-Increased seizure risk
-MAOI use in the last 2 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What conditions would cause a state of increased seizure risk?

A

-Epilepsy
-Eating disorders (anorexia, bulemia)
-Discontinuing alcohol, benzos, barbiturates or antieptileptic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the nonselective MAOIs?

A

Penelzine
Tranylcypromine
Isocarboxazid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the MOA of nonselective MAOIs?

A

Blocks breakdown of norepinephrine, serotonin (plus dopamine, epinephrine and tyramine) by inhibiting monoamine oxidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the indication for nonselective MAOIs?

A

Refractory depression or refractory anxiety disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the most common AE of MAOIs?

A

Orthostatic hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are other AEs of MAOIs?

A

Insomnia
Anxiety
Weight gain
Sexual dysfunction

21
Q

What is the crisis that can happen with MAOIs?

A

Hypertensive crisis following ingestion of foods high in tyramine (aged cheese, smoked/picked/cure meats/poultry/fish, red wine, draft beer and chocolates)

22
Q

What is the drug-drug interaction concern with MAOIs?

A

Serotonin syndrome with SSRIs, SNRIs, St John’s Wort, MDMA, cocaine, Meperidine, Tramadol and Dextromethorphan

23
Q

How long do you need to wait between switching between SSRIs and MAOIs?

A

2 weeks (5 for fluoxetine due to long half life)

24
Q

MAOI + TCAs may cause…

A

delirium and hypertension

25
Q

What are the serotonin receptor antagonists and agonists?

A

Trazodone and Nefazodone

26
Q

What is the MOA of Trazodone?

A

Post synaptic inhibitor, reuptake inhibition and serotonin agonist. Plus Alpha-1 adrenergic receptor antagonist

27
Q

What is trazodone indicated for

A

Antidepressant with anxiolytic and hypnotic effects (useful for insomnia)

28
Q

Low dose trazodone may be used as a ___ ____

A

sleep aid

29
Q

Unlike SSRIs, Trazodone does not affect _____

A

REM sleep or sexual side effects

30
Q

What is the most common AE of Trazodone?

A

Sedation

31
Q

What are other AEs of Trazodone?

A

-Dizzy
-Dry mouth
-Nausea
-Orthostatic hypotension
-HA
-Suicidality in children / young adults
-Cardiac arrhythmias

32
Q

What is a rare but classic AE of Trazodone?

A

Priapism

33
Q

What is the black box warning on Nefazodone?

A

Rare but serious fulmiant hepatitis

34
Q

What is Serotonin Syndrome?

A

Life threatening syndrome caused by increased serotonergic activity in the CNS

35
Q

When does Serotonin Syndrome most commonly occur?

A

Within 24 hours (especially six) of initiation of change in serotonergic drugs

36
Q

What medications/substances that are not mental health drugs can contribute to Serotonin Syndrome?

A

-St. John’s Wort
-MDMA
-Cocaine
-Amphetamines

37
Q

What categories of effects are seen in Serotonin Syndrome? (5)

A

-Cognitive
-Autonomic instability
-GI
-Neuromuscular hyperactivity
-Occular

38
Q

What cognitive effects are seen in Serotonin Syndrome?

A

-AMS
-Agitation
-Confusion
-Hallucinations
-Hypomania

39
Q

What autonomic instability effects are seen in Serotonin Syndrome?

A

-Hyperthermia
-Tachycardia
-Diaphoresis
-BP changes

40
Q

What GI effects are seen in Serotonin Syndrome?

A

-Diarrhea
-N/V
-Increased bowel sounds

41
Q

What neuromuscular effects are seen in Serotonin Syndrome?

A

-Spontaneous or inducible clonus
-Hypertonia (increased DTRs)
-Tremor
-Akathisia

42
Q

What occular effects are seen in Serotonin Syndrome?

A

-Mydriasis
-Dry mucus membranes
-Flushed skin

43
Q

How is Serotonin Syndrome diagnosed?

A

Clinical diagnosis with Hunter Criteria

44
Q

How is mild Serotonin Syndrome managed?

A
  1. Prompt discontinuation of offending drugs
  2. Supportive care with O2, IV fluids and Benzos
45
Q

Why are benzos used to treat Serotonin Syndrome?

A

-Reduce agitation, hyperthermia and correct mild increases in HR and BP

46
Q

How is moderate Serotonin Syndrome treated?

A

Same as mild plus Cyproheptadine

47
Q

What is Cyproheptadine?

A

Serotonin antagonist

48
Q

Should antipyretics be used in hyperthermia of Serotonin Syndrome?

A

No

Behavioral Health (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions