Anxiety Disorders 1 Flashcards
What is the definition of a panic attack?
A sudden, discrete episode of intense fear or discomfort
What is the usual timeline of a panic attack?
Usually peaks within ten mins, most end within 20-30 and rarely over an hour (but patients may feel anxious for hours after)
What is the hallmark sign of a panic attack?
Sense of impending fear or doom
What is the diagnostic criteria of a panic attack?
At least four of the following symptoms of sympathetic system overdrive
-Dizziness
-Trembling
-Choking feeling
-Parasthesias
-Sweating
-SOB
-CP/discomfort
-Chills or hot flashes
-Fear of losing control
-Fear of dying
-Palpitations / tachy
-Nausea or abd distress
-Depersonalization or derealization
Define depersonalization
Feeling detached from onself
Define derealization
Feeling of unreality
What is first line for panic attacks?
Benzos
What must you do in work up of panic attacks?
Rule out life threatening conditions (MI, thyrotoxicosis, etc)
Are panic attacks an anxiety disorder?
Not on their own, but are a feature of many anxiety disorders
What is the average age of onset of panic disorder?
Early to mid 20s
What adds to the risk of panic disorder
1st degree relative diagnosed
> 60% of patients with panic disorder also have ______
major depression
Panic disorder is more common in (gender)
Females
What are the diagnostic criteria for panic disorder?
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
Diagnostic criteria for panic disorder:
- At least ______________ (may or may not be related to a trigger)
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
2 recurrent, unexpected panic attack
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks ____________________
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
(may or may not be related to a trigger)
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least ___ of the following for at least _____:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
One, one month
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least one of the following for at least one month:
-___________________
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
Panic attacks are followed by concern about future attacks
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-___________
-Significant maladaptive behavior related to the attacks - Symptoms are not due to substance use, medical condition or another mental disorder
Persistent worry about the implications of the attacks (loss of control)
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-_________ - Symptoms are not due to substance use, medical condition or another mental disorder
Significant maladaptive behavior related to the attacks
Diagnostic criteria for panic disorder:
- At least 2 recurrent, unexpected panic attacks (may or may not be related to a trigger)
- At least one of the following for at least one month:
-Panic attacks are followed by concern about future attacks
-Persistent worry about the implications of the attacks (loss of control)
-Significant maladaptive behavior related to the attacks - ____________________
Symptoms are not due to substance use, medical condition or another mental disorder
What medical conditions could cause panic attack-like presentation?
Thyroid
Hypoglycemia
Cardiac
What is first line for long term treatment of panic disorder?
-SSRIs (can also use SNRIs)
-CBT
What is second line for long term management of panic disorder?
TCAs (if SSRIs are ineffective)
What is the most effective combo for treatment of panic disorder?
Pharmacotherapy and CBT
What is first line for acute panic disorder?
Benzodiazepines (Alprazolam, Clonezepam)
If necessary, you can start _____ and ____ for panic disorder, and then taper and discontinue ______
SSRIs and Benzos
Benzos
Define agoraphobia
Intense fear or anxiety about being in places or situations from which escape or obtaining help may be difficult
Agoraphobia may present as fear of ____
-Open spaces (such as bridges)
-Enclosed spaces
-Crowds
-Public transit
-Being away from home alone
Agoraphobia often presents with ____, but is now seen as a separate entity
Panic disorder
In agoraphobia, the triggering situation causes _______
fear or anxiety out of proportion to the potential danger
Agoraphobia symptoms must meet what three criteria
-At least six months
-Significant social or occupational dysfunction
-Not better explained by another disorder
What are risk factors for agoraphobia?
Strong genetic factor
Possibly follows a traumatic event
How is agoraphobia managed?
CBT and SSRIs (similar to panic disorder)
General Anxiety Disorder is more common in (gender)
Females
Onset of GAD symptoms usually occurs in (age)
early 20s
GAD Diagnostic Criteria:
- Excessive_____ a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
anxiety or worry
GAD Diagnostic Criteria:
- Excessive anxiety or worry_______ about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
a majority of days, for at least six months
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about______
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
various aspects of life
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually _______ - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
out of proportion to the event
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least ___symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
3
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
_______ - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
-Fatigue
-Restlessness
-Difficulty concentrating
-Muscle tension
-Sleep disturbance
-Irritability
-Shakiness
-HA
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not _____
- Symptoms cause significant occupational or social dysfunction
- Not due to medical illness or substance abuse
episodic
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant______
- Not due to medical illness or substance abuse
occupational or socal dysfunction
GAD Diagnostic Criteria:
- Excessive anxiety or worry a majority of days for at least six months about various aspects of life
-The anxiety is usually out of proportion to the event - Associated with at least three symptoms:
-Fatigue, restlessness, difficulty concentrating, muscle tension, sleep disturbance, irritability, shakiness, headaches - Anxiety is not episodic
- Symptoms cause significant occupational or social dysfunction
- Not due to ______
medical illness or substance abuse
What is first line tx for GAD?
SSRIs and CBT
What can be used as an alternative to SSRIs in GAD?
SNRIs
What med can be an adjunct to SSRIs in GAD?
Buspirone
What is a benefit of Buspirone in GAD?
It does not cause sedation or potentiate CNS depression of alcohol (almost no abuse or addiction potential)
What is the ideal combination treatment for GAD?
CBT + pharmacotherapy
What can be used for short term bridging in GAD?
Benzos
What alternative meds can be used in GAD?
Beta blockers or TCAs
What is the MOA of Buspirone?
Partial serotonin receptor (5HT-1A0 agonist and dopamine receptor agonist
How long does Buspirone take to become effective
1-2 weeks
What are adverse effects of Buspirone?
HA
Nausea
Dizziness
RLS
Extrapyramidal symptoms