BBB penetrability Flashcards by gluteus mcbutterson

Q

sulfonamides

A

excellent with or without inflammation

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Q

chloramphenicol

A

excellent with or without inflammation

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Q

trimethroprim

A

excellent with or without inflammation

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Q

metronidazole

A

excellent with or without inflammation

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Q

rifampicin

A

excellent with or without inflammation

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Q

isoniazid

A

excellent with or without inflammation

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Q

fluconazole

A

excellent with or without inflammation

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Q

flucystosine

A

excellent with or without inflammation

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Q

penicillins

A

good only with inflammation

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Q

cephalosporins:

cefuroxime (2nd gen)

A

good only with inflammation

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Q

cephalosporins:

3rd gen parenteral (except cefoperazone)

A

good only with inflammation

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Q

4th gen cephalosporins

A

good only with inflammation

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Q

imipinem + cilastatin

A

good only with inflammation

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Q

meropenem

A

good only with inflammation

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Q

aztreonam

A

good only with inflammation

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Q

ciprofloxacin

A

good only with inflammation

Q

vancomycin

A

good only with inflammation

Q

aminoglycosides

A

minimal or not good even with inflammation

Q

tetracyclines

A

minimal or not good even with inflammation

Q

lincosamides

A

minimal or not good even with inflammation

Q

macrolides

A

minimal or not good even with inflammation

Q

polymixins

A

no passage even with inflammation

Q

1st gen cephalosporins

A

no passage even with inflammation

Q

2nd gen cephalosporins

A

no passage even with inflammation

Q

amphotericin B

A

no passage even with inflammation