BBB penetrability Flashcards

1
Q

sulfonamides

A

excellent with or without inflammation

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2
Q

chloramphenicol

A

excellent with or without inflammation

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3
Q

trimethroprim

A

excellent with or without inflammation

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4
Q

metronidazole

A

excellent with or without inflammation

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5
Q

rifampicin

A

excellent with or without inflammation

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6
Q

isoniazid

A

excellent with or without inflammation

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7
Q

fluconazole

A

excellent with or without inflammation

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8
Q

flucystosine

A

excellent with or without inflammation

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9
Q

penicillins

A

good only with inflammation

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10
Q

cephalosporins:

cefuroxime (2nd gen)

A

good only with inflammation

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11
Q

cephalosporins:

3rd gen parenteral (except cefoperazone)

A

good only with inflammation

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12
Q

4th gen cephalosporins

A

good only with inflammation

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13
Q

imipinem + cilastatin

A

good only with inflammation

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14
Q

meropenem

A

good only with inflammation

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15
Q

aztreonam

A

good only with inflammation

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16
Q

ciprofloxacin

A

good only with inflammation

17
Q

vancomycin

A

good only with inflammation

18
Q

aminoglycosides

A

minimal or not good even with inflammation

19
Q

tetracyclines

A

minimal or not good even with inflammation

20
Q

lincosamides

A

minimal or not good even with inflammation

21
Q

macrolides

A

minimal or not good even with inflammation

22
Q

polymixins

A

no passage even with inflammation

23
Q

1st gen cephalosporins

A

no passage even with inflammation

24
Q

2nd gen cephalosporins

A

no passage even with inflammation

25
Q

amphotericin B

A

no passage even with inflammation