Basic science Flashcards

1
Q

isotonic contraction

does tension or length stay constant?

A

tension constant

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2
Q

types of motor neurones in muscle spindle

A

gamma

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3
Q

skeletal muscle cell membrane

A

sarcolemma

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4
Q

which type of collagen in fibrocartilage

A

type 1

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5
Q

osteoprogenitor cells

A

pool of reserve osteoblasts

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6
Q

what do osteoblasts secrete?

A

osteoid

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7
Q

what hydrolyses Ach to terminate neuromuscular transmission

A

AchE

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8
Q

what is Lambert-Eaton Myasthenia syndrome assoc with

A

muscle weakness in limbs

SCC of lung

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9
Q

Skeletal NMJ
what causes fusion of Ach vesicles with presynaptic membrane?
what enters the cell when 2 mols of Ach bind and the gate opens?

A

Ca2+ causes fusion of Ach vesicles with the presynaptic membrane

2 mols of Ach bind, opening the gate, and Na+ enters the cell (K+ exits)

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10
Q

Myasthenia gravis
F or M?
25% have??

A

F

25% have thymoma

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11
Q

what does botulinum toxin irreversibly inhibit

A

Ach release

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12
Q

what do curare like compounds interfere with

A

post synaptic action of Ach

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13
Q

are TNF-alpha and IL1 involved in catabolism or anabolism?

A

catabolism

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14
Q

what cells produce and maintain the ECM

A

chondrocytes

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15
Q

property of proteoglycans

A

compressive

assoc with weight bearing

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16
Q

joint lubrication

A

hyaluronic acid

lubricin