Basic pharmacology terms

Question 1

The movement of particles from the G.I. tract to body fluids

Answer 1

Absorption

Question 2

Drugs that block a response

Answer 2

Antagonists

Question 3

Process by which the drug becomes available to body fluids and body tissue

Answer 3

Distribution

Question 4

Large initial dose given to achieve a rapid minimum effective concentration in the plasma

Answer 4

Loading dose

Question 5

The highest plasma concentration of a drug at a specific time

Answer 5

Peak drug.level

Question 6

The process of drug movement to achieve action

Answer 6

Pharmacokinetic

Question 7

Drug concentration in plasma should be between the minimum effective concentration in the plasma and the minimum toxic concentration

Answer 7

Therapeutic range

Question 8

Requires a carrier, an enzyme or protein to move the drug against a concentration gradient

Answer 8

Active absorption

Question 9

(Subcategory of absorption) the percentage of a drug that reaches systemic circulation

Answer 9

Bioavailability

Question 10

The length of time the drug has pharmacologic effect

Answer 10

Duration of action

Question 11

The time it takes to reach the minimum effective concentration (MEC) after a drug is administered

Answer 11

Onset

Question 12

The first phase of drug action

Answer 12

Pharmaceutics

Question 13

The process by which cells carry a drug across the cell membrane by engulfing the particles

Answer 13

Pinocytosis

Question 14

The lowest plasma concentration of a drug. The _______measures delete which drug is eliminated; levels are immediately before the next dose of the drug is given

Answer 14

Trough level

Question 15

More severe than side effects, always undesirable

Answer 15

Adverse reactions

Question 16

The breakdown of a tablet into smaller particles

Answer 16

Disintegration

Question 17

The process in which a drug passes to the liver first

Answer 17

First-pass effect

Question 18

Occurs mostly by diffusion

Answer 18

Passive absorption

Question 19

The study of a drug concentration and its effects on the body

Answer 19

Pharmacodynamic phase

Question 20

The portion of a drug that is bound is inactive because it is not available to the receptors

Answer 20

Protein-binding effect

Question 21

Drugs that produce a response

Answer 21

Agonists

Question 22

The dissolving of smaller particles in the G.I. fluid prior to absorption

Answer 22

Dissolution

Question 23

The time it takes one-half of the drug concentration to be eliminated; a drug goes through several half-lives before 90% of the drug is eliminated

Answer 23

Half-life

Question 24

The point at which a drug reaches its highest blood or plasma concentration

Answer 24

Peak action

Question 25

The effect of a drug action that varies from a predicted drug response of genetic factors that influence or hereditary influence

Answer 25

Pharmacogenetics

Question 26

Physiologic effects not related to desired drugs effects

Answer 26

Side effects