Baek Paper Flashcards
1
Q
Lrp does what to T1 fimbriae synthesis?
A
Activates
2
Q
Lrp regulates what?
A
FimZ, a positive regulator of T1 fimbriae production
3
Q
FimZ
A
Binds promoter to activate expression
4
Q
FimY
A
Transcriptional activator
5
Q
FimW
A
Negative regulator (represses fimY transcription)
6
Q
FimU
A
Arginine tRNA gene (post transcriptional regulator)
7
Q
When is the fimA promoter inactive?
A
In the absence or overexpression of Lrp
8
Q
Lrp binding motifs 1 and 2 do what?
A
Mediate activation and depression of T1 fimbriae gene expression
9
Q
Low Lrp=?
A
High Fimz and T1 fimbriae production
10
Q
High Lrp = ?
A
Low FimZ = no T1 fimbriae production
11
Q
Which motif is important for repression?
A
Motif 2
