Bacteria Clinical Presentations

Question 1

Corynebacterium Diptheriae

Answer 1

Pseudomembranous pharyngitis, lymphadenopathy, cardiomyopathy/heart failure, neuropathy/paralysis

Question 2

Pseudomonas Aeruginosa

Answer 2

Pneumonia, sepsis (black lesions on skin), external otitis, UTI, osteomyelitis, hot tub folliculitis

Question 3

Shigella

Answer 3

Dystenery (GI mucosal damage), HUS (ST enhanced cytokine release)

Question 4

EHEC (Enterohemorrhagic E. Coli - 0157:H7)

Answer 4

Dystentery, HUS (enchanced cytokine release)

Question 5

ETEC (Enterotoxigenic E. Coli) - Type 1

Answer 5

Watery diarrhea

Question 6

ETEC (Enterotoxigenic E. Coli) - Type 2

Answer 6

Watery diarrhea

Question 7

Yersinia Enterocolitica

Answer 7

Dysentery, mesenteric adenitis (mimics Crohn’s or appendicitis)

Question 8

Bacillus anthracis

Answer 8

Cutaneous anthrax (black eschar that can progress to bacteremia), pulmonary anthrax (fever, pulmonary hemorrhage, mediastinitis, shock)

Question 9

Vibrio cholerae

Answer 9

Voluminous rice-water diarrhea

Question 10

Bordetella Pertussis

Answer 10

Children: whooping cough (cough on expiration, whoop on inspiration), adults: 100 day cough

Question 11

Clostridium Tetani

Answer 11

Muscle rigidity, trismus, risus sardonicus

Question 12

Clostridium botulinum

Answer 12

Diplopia, dysphagia, dysphonia, flaccid paralysis (floppy baby)

Question 13

Clostridium perfringens

Answer 13

Myonerosis (gas gangrene), hemolysis, late-onset watery diarrhea

Question 14

Mycobacterium leprae

Answer 14

Leprosy: lepromatous (diffuse lesions over skin, communicable, humoral Th2 response, low cell-mediated immunity) OR tuberculoid (limited hypoesthetic skin-plaques, high cell-mediated immunity, Th1)

Question 15

EIEC (Enteroinvasive E. Coli)

Answer 15

Dysentery

Question 16

EPEC (Enteropediatric E. Coli)

Answer 16

Diarrhea in children

Question 17

Haemophilus influenzae

Answer 17

Epiglottitis (fever, dysphagia, drooling, difficulty breathing due to edematous “cherry red” epiglottis), meningitis, otitis media, pneumonia

Question 18

Brucella

Answer 18

Brucellosis: fever, muscle pain, sweating

Question 19

Neisseria Gonorrhoeae

Answer 19

Genitourinary infections (PID, Urethritis, cervicitis, prostatitis, Fitz-Hugh Curtis syndrome), neonatal conjunctivitis, septic arthritis