BABESIA SPP. Flashcards
phylum of Babesia spp.
Apicomplexa
Order of Babesia spp.
Piroplasmida
morphology of babesia spp.
pleomorphic
True or False. Babesia spp. vary in size and shape
True
what stage is present to both babesia and plasmodium
trophozoite forms
True or False. There is hemozoin in babesia spp.
False
There is no presence of hemozoin in Babesia spp.
Is there a presence of pre-erythrocytic stage in Babesia spp.
No
who discovered Babesia spp.
Victor Babes
on what yeat was babesia discovered
1888
old name of Babesia
Haematococcus bovis
these two individuals associated Babesia spp. as a zoonotic parasite
Theobald Smith and Fred Kilborne (1893)
Babesia spp. is counted as a zoonotic parasite. thus, they invade who?
wild and domestic animals
Who serves as an accidental host
Man
these have no primary involvement in the life cycle or transmission of Babesia spp
Man
State the two clinical isolates of Babesia
Babesia microti
Babesia divergens
due to microti’s ribosomal RNA, it fits more into what genus
Theileria
Diagnostic feature of Babesiosis is
trophozoite stage
shape of Babesia spp trophoziotes
Round oval pear-shaped
true or false. microti and divergens have the same morphological forms
True
number of merozoites in Babesia
2-4 merozoites
this is another term for resembling four trophozoites attached by chromatin dots
“Maltese cross” appearance
Babesia definitive host
Vector (tick)
size of babesia trophozoites
2-4 um
where do merozoites develop?
within the RBC (as trophozoite matures)
this type of reproduction takes place WITHIN its vector
sexual reproduction (sporogony)
this type of reproduction takes place WITHIN its host
Asexual reproduction (merogony)
Ixodes dammini is commonly known as
Ixodes scapularis
Primary intermediate host
Peromyscus leucopus
MOT of babesia spp
Bite of infected Ixodes ticks
this is the process of spore and sporozoite production via sexual reproduction
sporogony
How many hours must the uninfected host be in contact with the tick’s saliva for it to be transmitted to the intermediate/accidental host
at least 12 hours
Person infected with Babesia is likely bitten by an infected tick for how many weeks (give the range) before they started showing symptoms
1-4 weeks
More severe clinical symptoms of Babesiosis
Hepatosplenomegaly
Hemolytic anemia
Thrombocytopenia
Laboratory Diagnosis of Babesiosis
Microscopy
Thick and Think Blood Smear
Indirect Immunofluorescent Antibody
Immunoblot
Polymerase Chain Reaction (PCR)
state babesia’s prodromal symptoms
fever
myalgias
headache
fatigue
chills
weakness
sweating
arthralgias
This lab diagnosis is used to differentiate between microti and divergens
Polymerase Chain Reaction (PCR)
State the Factors considered in choosing therapy
Patient’s age
Immune Status
Glucose-6-phosphate dehydrogenase deficiency
clinical symptoms
this combination of drugs is used for severe cases
Clindamycin & Quinine
this combination of drugs is used for mild to moderate cases
Atovaquone & Azithromycin
State the drugs used for animals
Diminazene aceturate
pentamidine
Pyrimethamine
