B6.055 Clinical Implications of Osteoporosis Flashcards
most common metabolic bone disease in the elderly
osteoporosis
difference between male and female bone mass
men have 30% more bone mass
difference between AA and Caucasian bone mass
AA get 10% higher peak bone mass
risk of hip fracture in white and black women in the US
risk by age 90
- 3% in white women
- 3% in black women
prevalence of osteoporosis worldwide
8.9 million fractures annually
fracture every 3 seconds
200 million women worldwide
75% in patients 65 or over
epidemiology of osteoporosis in the US
52 million women and men 50 or older have osteoporosis OR osteopenia (14 million osteoporosis)
50% of women over age 50 will sustain a fracture in their lifetime
what areas are measure in a DXA scan
radius
lumbar spine
greater trochanter
how much is fracture risk increased with a drop of 1 SD in BMD
2.6%
how much is fracture risk increased with a drop of 2.5 SDs in BMD
10%
not linear
most common fractures
- distal forearm
- hip
- spine
fracture risk factors
- fall risk
- BMD
- architecture and geometry of bones
screening of BMD
start @ 65
every 2 years get a DXA
every year if on osteoporosis therapy
can start earlier with justification
risk factors for osteoporosis in men
hypogonadism
alcoholism
glucocorticoid use
what is the minimum amt of steroid that can begin bone loss
7.5 mg qd for a month
mortality post hip fracture in men vs women
men 2x higher mortality
