B6.035 Prework 1: HSP

Question 1

purpura

Answer 1

red or purple spots on the skin that do not blanch with pressure
bleeding under skin showing through
3-10 mm in size

Question 2

petechia

Answer 2

< 3 mm

Question 3

ecchymoses

Answer 3

> 10 mm

Question 4

differential diagnosis of purpura

Answer 4

infection
platelet disorders
vasculitis

Question 5

infection associated purpura

Answer 5

fevers, likely leukocytosis, tachycardia, tachypnea

• sepsis/ DIC
• meningococcemia

Question 6

platelet disorder associated purpura

Answer 6

thrombocytopenic purpura
low platelet count and absence of signs of infection
-ITP
-TTP

Question 7

vasculitis associated purpura

Answer 7

platelet count normal
occasional fevers and constitutional symptoms with vasculitis due to inflammatory cascade
no instability of vitals
-immune complex vasculitis
-drug induced vasculitis
-ANCA associated vasculitis

Question 8

bowel angina

Answer 8

abdominal pain that worsens with eating due to poor blood supply to the intestines
in HSP vessels are occluded bc of inflammation
patients have signs of GI bleed and pain

Question 9

hematuria w HSP

Answer 9

if kidneys involved, commonly present in HSP
positive blood on urine dipstick and microscopy
sometimes will have proteinuria

Question 10

other causes of hematuria in children

Answer 10

traumatic collection
IgA nephropathy
benign familial hematuria
myoglobinuria

Question 11

arthritis

Answer 11

inflammation of the joint

• includes pain, swelling, heat, redness
• isolated pain w/o other signs is arthralgia, not arthritis

Question 12

HSP associated arthritis

Answer 12

most commonly ankle, followed by knees, wrists, and elbows

Question 13

common causes of arthritis in kids

Answer 13

reactive (after viral resp infection)

juvenile RA