B6.035 HSP Flashcards
1
Q
first step in pt management when presenting w palpable purpura
A
CBC - rule out other causes
2
Q
bad signs for HSP prognosis
A
older pt
HTN at onset
crescent on biopsy
3
Q
why not use NSAIDs in HSP?
A
bleeding (platelet inhibition)
exacerbate GI symptoms
kidney injury
4
Q
does HSP involve lungs?
A
no
anti-GBM does
5
Q
organ specific autoimmune disease
A
autoantibodies directly bind to and injure target organs
6
Q
systemic autoimmune diseases
A
autoantibodies react with free molecules and cell surface and nucleoprotein antigens, forming immune complexes