B6.030 Prework: Skin Cancers

Question 1

features of keratinocytes on histo

Answer 1

main cells in epidermis (95%)
have intracellular bridges
confer tensile strength

Question 2

features of melanocytes on histo

Answer 2

located in basal layer of epidermis
no intracellular bridges
smaller nuclei than keratinocytes
basophilic

Question 3

macules/patches

Answer 3

flat, circumscribed lesion
distinguished from surrounding skin by color
macules < 5mm
patches > 5mm

Question 4

papule/nodule

Answer 4

raised dome shaped or flat topped lesion
papules < 5mm
nodules >5mm

Question 5

plaque

Answer 5

raised flat topped lesion

usually >5m across

Question 6

acanthosis

Answer 6

thickening of epidermis

Question 7

acantholysis

Answer 7

keratinocytes falling apart

Question 8

hyperkeratosis

Answer 8

thickening of corneum due to chronic irritation

Question 9

parakeratosis

Answer 9

hyperkeratosis with retained nuclei