B6.016 Soft Tissue Tumors (General Features)

Question 1

definition of a soft tissue tumor

Answer 1

mesenchymal proliferations that occur in nonepithelial, extraskeletal tissues of the body

Question 2

locations of soft tissue tumors

Answer 2

40% lower extremity
30% trunk and retroperitoneum
20% upper extremity
10% head and neck

Question 3

classification system of soft tissue tumors

Answer 3

based on type of tissue they arise from

some have specific chromosomal abnormalities and genetic rearrangements that can be used as markers

Question 4

categories of soft tissue tumors

Answer 4

1. benign tumors or tumor-like lesions
2. intermediate malignancy
3. malignant (sarcomas)

Question 5

characterize benign soft tissue tumors

Answer 5

most common
rarely recur
do not metastasize

Question 6

characterize intermediate malignancy

Answer 6

frequently recur

rarely metastasize

Question 7

characterize malignant tumors (sarcomas)

Answer 7

frequently recur

frequently metastasize

Question 8

sarcoma treatment factors

Answer 8

type and site
grade (histological)
stage (clinical)

Question 9

how is a tumor graded

Answer 9

low, intermediate, high

based on differentiation, mitoses, and % necrosis

Question 10

in general what types of tumors have a better prognosis

Answer 10

tumors arising in superficial locations are detected earlier and have a better prognosis than deep seated tumors

Question 11

tissue types

Answer 11

adipose
fibrous
smooth muscle
skeletal muscle
vascular
peripheral nerve sheath
synovial