B6-077 Bone Tumors

Question 1

all bone tumors derive from what cell origin?

Answer 1

osteoblasts

Question 2

pain at night relieved by NSAIDs

Answer 2

osteoid osteoma

Question 3

pain unresponsive to NSAIDs

Answer 3

osteoblastoma

Question 4

benign tumor that prefers the axial skeleton

Answer 4

osteoblastoma

Question 5

occurs in children
typically long bones
benign mass

Answer 5

osteoid osteoma

Question 6

bimodal distribution
likes long bones and face bones

Answer 6

osteosarcoma

Question 7

codman’s triangle

Answer 7

conventional osteosarcoma

Question 8

treatment of osteoid osteoma

Answer 8

radiofrequency ablation

Question 9

treatment of osteoblastoma

Answer 9

curettage or resection

Question 10

osteosarcoma treatment

Answer 10

wide resection and chemotherapy

Question 11

<2 cm bony mass

Answer 11

osteoid osteoma

Question 12

> 2cm bony mass

Answer 12

osteoblastoma

Question 13

cartilage tumors in the digits are nearly always

Answer 13

benign

Question 14

cartilage tumors in the pelvis and axial skeleton are nearly always

Answer 14

malignant

Question 15

lobules with reactive bone at periphery

Answer 15

enchondroma

Question 16

chondroblasts permeate existing bone

Answer 16

chondrosarcoma

Question 17

low-grade chondrosarcoma in the long bones is

Answer 17

atypical cartilaginous tumor

Question 18

atypical cartilaginous tumor treatment

Answer 18

curettage

Question 19

chondrosarcoma treatment

Answer 19

wide resection

**does not respond to chemo

Question 20

medullary continuity

Answer 20

osteochondroma

Question 21

lateral bony projections of growth plate
recapitulates growth plate

Answer 21

osteochondroma

Question 22

enchondroma leaves the cortex […]

Answer 22

intact

Question 23

fibrous dysplasia is caused by

Answer 23

congenital somatic mutation

Question 24

is fibrous dysplasia well differentiated?

Answer 24

yes

Question 25

streamers of bone

Answer 25

low grade central osteosarcoma

Question 26

spicules of bone in continuity with bone

Answer 26

fibrous dysplasia

Question 27

is low grade central osteosarcoma well differentiated?

Answer 27

no, its permeative

Question 28

treatment of fibrous dysplasia

Answer 28

none

Question 29

low grade central osteosarcoma treatment

Answer 29

wide resection, no chemo

Question 30

occurs in 10% of population in children, around knee benign, usually go away on there own

Answer 30

non-ossifying fibroma

Question 31

affects skeletally mature patients at epiphysis

Answer 31

giant cell tumor of bone

Question 32

storiform architecture foamy histiocytes

Answer 32

non-ossifying fibroma

Question 33

huge multinucleate giant cells nuclei of cells in stroma look like nuclei of the giant cells

Answer 33

giant cell tumor of bone

Question 34

cyst that is well demarcated and doesn't really expand bone

Answer 34

simple bone cyst

Question 35

cyst that rapidly expands bone

Answer 35

Aneursymal Bone Cyst

Question 36

serous filled cyst

Answer 36

simple bone cyst

Question 37

blood filled cyst

Answer 37

Aneursymal Bone Cyst

Question 38

cyst that is a cellular tumor

Answer 38

Aneursymal Bone Cyst

Question 39

cyst that is an acellular tumor

Answer 39

simple bone cyst

Question 40

normal sized giant cells spindle cells bone spiculations

Answer 40

Aneursymal Bone Cyst

Question 41

osteomyelitis is often located in the

Answer 41

metaphysis

Question 42

small round cell tumor

Answer 42

Ewing sarcoma

Question 43

EWSR1-FLI1

Answer 43

ewing sarcoma

Question 44

normal bone with lymphocytic infiltrate

Answer 44

osteomyelitis

Question 45

giant cells spindle cells in storiform pattern foamy macrophages metadiaphyseal region

Answer 45

non-ossifying fibroma

Question 46

necrotic bone neutrophils (lymphocytic infiltate)

Answer 46

osteomyelitis

Question 47

blood circulation is richest where?

Answer 47

near growth plate

Question 48

osteomyelitis in a child is likely to present in what part of bone?

Answer 48

near growth plate

Question 49

cartilage neoplasms of the digits are likely to be

Answer 49

enchondromas

Question 50

multinucleated giant cells stromal cells have nuclei that appear cytologically similar

Answer 50

giant cell tumor of bone

Question 51

marrow continuity

Answer 51

osteochondroma

Question 52

largely acellular (small lesion, big cyst) mostly fibrin/fibrous walls

Answer 52

simple bone cyst

Question 53

most common benign bone tumor typically occurs in males <25

Answer 53

osteochondroma

Question 54

benign tumor that occurs in the metaphysis of long bones

Answer 54

osteochondroma

Question 55

continuous with marrow space covered by cartilage cap

Answer 55

osteochondroma

Question 56

.

Answer 56

.

Question 57

benign tumor that occurs in the cortex of long bones adults <25 males > females

Answer 57

osteoid osteoma

Question 58

presents as bone pain relieved by NSAIDs bony mass <2cm with radiolucent core

Answer 58

osteoid osteoma

Question 59

typically occurs in the vertebrae males > females

Answer 59

osteoblastoma

Question 60

bony mass >2cm pain unresponsive to NSAIDs

Answer 60

osteoblastoma

Question 61

typically occurs in the medulla of small bones of hand and feet benign tumor of cartilage

Answer 61

chondroma

Question 62

benign tumor that occurs in the epiphysis of long bones (knee region) 20-40 year olds

Answer 62

giant cell tumor

Question 63

osteosarcoma typically occurs in what age range?

Answer 63

males <20 years

Question 64

malignant tumor occurring in metaphysis of long bone

Answer 64

osteosarcoma

Question 65

presents as painful enlarging mass or pathologic fracture pleomorphic, osteoid producing cells

Answer 65

osteosarcoma

Question 66

malignant tumor more commonly occurring in adults > 50

Answer 66

chondrosarcoma

Question 67

malignant tumor that commonly occurs in the medulla of pelvis, proximal femur, and humerus

Answer 67

chondrosarcoma

Question 68

usually lytic, with intralesional calcifications, endosteal erosion, and cortex breach malignant tumor of chondrocytes

Answer 68

chondrosarcoma

Question 69

generally occurs in patients <15 in the diaphysis of long bones (especially femur)

Answer 69

Ewing sarcoma

Question 70

anaplastic small blue cells of mesenchymal origin

Answer 70

Ewing sarcoma