B-lactamase Inhibitors Flashcards
1
Q
B-lactamase inhibitor drugs
A
clavulanate
sulbactam
taxobactam
2
Q
Mechanism of action
A
No direct antibacterial activity;
they are suicide inactivators of B-lactamases, pseudosubstrates that allow for co-administration of penicillins to reach PBPs in bacteria
3
Q
Amoxicillin + clavulanate
A
H. influenzae, oral use
4
Q
Ampicillin + sulbactam
A
Bite wounds and diabetic foot ulcers, parenteral use
5
Q
Piperacillin + tazobactam
A
Nosocomial pneumonia, parenteral use
